Skip to content

The effect of exercise and curcumin on hemodialysis disease

The effect of cimbination of exercise and curcumin supplementation on serum ferritin and serum albumin in hemodialysis patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200819048461N2
Enrollment
80
Registered
2022-12-21
Start date
2023-01-03
Completion date
Unknown
Last updated
2023-03-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

End stage renal disease. Chronic kidney disease, stage 5

Interventions

Intervention 1: The first intervention group :the experimental group will do 3 sessions of 45-minute exercise program per week at home on non-dialysis days with the simultaneous supervision of an onli

Sponsors

Islamic Azad University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Age between 18 and 80 years More than three months of dialysis experience Having a three-time hemodialysis program No heart attack and stroke in the past three months Having the ability to communicate with others The permission of the attending physician to practice be clinically stable

Exclusion criteria

Exclusion criteria: Unstable heart condition (angina, congestive heart failure, severe arterial stenosis, uncontrolled arrhythmias, etc.) Active infection or acute medical illness Hemodynamic instability, unstable blood sugar unable to exercise (lower limb amputation without prosthesis) Having severe skeletal-muscular pain at rest or minimal activity Having shortness of breath while resting or with daily activities Allergy or insensitivity to turmeric

Design outcomes

Primary

MeasureTime frame
The normal level of ferritin in serum is between 10 and 300 nanograms per milliliter, and ferritin levels above 200 nanograms per milliliter in women and above 300 nanograms per milliliter in men have been diagnosed as abnormal. Serum ferritin levels in hemodialysis patients measurement of serum ferritin in the bloodstream can be useful for monitoring the progress of hemodialysis disease. Timepoint: Ferritin measurement of the subjects' blood was done in two stages, the first stage in the initial blood sampling, i.e. 24 hours before the start of the exercise protocol and curcumin supplementation, and the second stage in the blood sample of the last stage, three months after the last exercise session and the last curcumin intake a done. Method of measurement: To measure serum ferritin, it was measured and recorded using the ARKA kit by ELISA method (Enzyme-linked immunoadsorbent assay).;Serum albumin level, the normal level of serum albumin is between 4.3 and 4.5 grams per deciliter, and hemodialysis patients have low albumin levels. Measuring the amount of serum albumin in the bloodstream can be useful for monitoring the progress of hemodialysis patients. Timepoint: Measuring the blood albumin of the subjects in two stages, the first stage in the initial blood sampling, i.e. 24 hours before the start of the exercise protocol and taking curcumin supplement and the second stage, in the final stage blood sampling, three months after the last session of sports training and the last curcumin intake a done . Method of measurement: The amount of albumin was measured and recorded by the Bionik laboratory kit, using the autoanalyzer olympus model AU made in Iran.

Secondary

MeasureTime frame
Functional status. Timepoint: Before starting exercise and taking curcumin and three months later. Method of measurement: 6-minute walking test.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMehsa Soleimani Sadeh

Islamic Azad University

soleymanymahsa1375@gmail.com+98 31 5243 5855

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026