The effect of Clindamycin and Lactobacilli suppository on in-vitro fertilization (IVF) results

Comparison of the effect of Clindamycin suppository and Lactobacilli suppository in vaginal microbiome on in-vitro fertilization (IVF) in patients candidate for embryo transfer referring to Omid clinic, Hamedan: single blind randomized clinical trial

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200819048456N1

Enrollment

108

Registered

2021-01-06

Start date

2020-11-21

Completion date

Unknown

Last updated

2021-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility. Female infertility

Interventions

Intervention 1: Intervention group: clindamycin suppository. Intervention 2: Intervention group: lactobacilli suppository. Intervention 3: Control group: placebo.

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Patients candidate for IVF referring to Omid clinic, Hamedan, Iran

Exclusion criteria

Exclusion criteria: Poor responder Severe male infertility

Design outcomes

Primary

Measure	Time frame
Implantation rate. Timepoint: 2 weeks. Method of measurement: Sonography.	—

Secondary

Measure	Time frame
Prelabor rupture of membranes. Timepoint: 22 to 37 weeks. Method of measurement: Yes/ no questionnaire.;Life birth rate. Timepoint: 38 weeks. Method of measurement: Yes/ no questionnaire.;Abortion rate. Timepoint: 12 weeks. Method of measurement: Yes/ no questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactRoghayeh Anvari aliabad

Hamedan University of Medical Sciences

anvar_anvari@yahoo.com+98 81 3827 8080

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026