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Antimicrobial Efficacy of Darpomin Mouthwash and Clinical Efficacy on Gingivitis Control

Antimicrobial Efficacy of Darpomin Mouthwash (Cinnamon and Mentha Pulegium Essential Oils) and Clinical Efficacy on Gingivitis Control in Comparsion with Chlorhexidine Mouthwash in Patients undergoing Orthodontic Treatment with Fixed Appliances

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200815048419N1
Enrollment
45
Registered
2020-09-14
Start date
2020-09-21
Completion date
Unknown
Last updated
2020-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gingivitis. Chronic gingivitis, plaque induced

Interventions

Intervention 1: Control group: Patients receive mechanical hygiene kits (including orthodontic toothbrush and floss, interdental toothbrush) and are instructed to brush twice a day, morning and evenin

Sponsors

Ahvaz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
10 Years to No maximum

Inclusion criteria

Inclusion criteria: Presence of at least 20 natural teeth Good general health A mean plaque index greater than 1.5 Presence of gingivitis concurrent with fixed orthodontic appliances and associated with visible plaque A minimum of eight sites with bleeding on probing (BOP)

Exclusion criteria

Exclusion criteria: Presence of any systemic disease Evidence of destructive periodontal disease Use of drugs that could affect the periodontium Antibiotic therapy during the previous 3 months Pregnancy and breast-feeding Smoking Continuous use of mouthwashes containing chemical agents during the previous 3 months History of allergies to toothpaste, mouthwash, or herbal medicine

Design outcomes

Primary

MeasureTime frame
Measurement of Visible Plaque Index (VPI). The Presence of visible dental plaque along the gingival margin is evaluated on 4 Surfaces (mesial, distal, buccal and lingual) of each tooth and is presented as a percentage of the total examined oral surfaces. Timepoint: The first day of study (before the intervention) and 15 days after using mouthwash. Method of measurement: Observation by the naked eye under the sufficient light.;Measurement of Gingival Bleeding Index (GBI). each tooth is probed in 6 areas (mesial, middle, and distal on both buccal and lingual surfaces). The number of bleeding points is presented as a percentage of the total probed points in the mouth. Timepoint: The first day of study (before the intervention) and 15 days after using mouthwash. Method of measurement: WHO probe.;The number of colonies of oral bacteria grown in the culture medium. Timepoint: The first day of study (before the intervention) and 15 days after using mouthwash. Method of measurement: Counting by the naked eye under the sufficient light.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactOzra Niknam

Ahvaz University of Medical Sciences

ozra.niknam@gmail.com+98 61 3320 5168

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026