Evaluation of the effect of aerobic exercise in patients with hypertension

The effect of 12 weeks of aerobic exercise on a selection of symptoms of heart failure in women patients with hypertension

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200815048410N1

Enrollment

Registered

2020-08-18

Start date

2018-09-23

Completion date

Unknown

Last updated

2020-09-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Women with hypertension with an age range of 50 to 70 years, according to the seventh report of the Joint National Committee for the Prevention, Diagnosis, Measurement and Treatment of Hypertension, in stage 1 hypertension (systolic pressure 159-140 and diastolic pressure 99-90 mm Mercury). Essential (primary) hypertension

Interventions

Intervention 1: The training program consisted of 12 weeks of aerobic exercise with an intensity of 30 to 60% of the maximum heart rate, 45 minutes per session and 3 sessions per week. Intervention 2:

Eligibility

Sex/Gender

Female

Age

50 Years to 70 Years

Inclusion criteria

Inclusion criteria: They were between 50 and 70 years old. They had high blood pressure They had no history of heart or balloon surgery Not diabetic Non-athletes All subjects are in menopause

Exclusion criteria

Exclusion criteria: Exercise 6 months before the research Cardiovascular diseases Use of non-hypertensive drugs Unseen 3 more sessions during the investigation

Design outcomes

Primary

Measure	Time frame
NT-proBNP concentration. Timepoint: 24 hours before the start of aerobic exercise and 24 hours after 12 weeks of exercise. Method of measurement: ELISA kit made by the Chinese company Casabio to measure the amount of N-terminal pro – B-type natriuretic peptide (NT-proBNP).;CT-1 concentration. Timepoint: 24 hours before the start of aerobic exercise and 24 hours after 12 weeks of exercise. Method of measurement: ELISA kit made by the Chinese company Casabio to measure the amount Cardiotropin-1 ( CT-1).;TGF-ß1 concentration. Timepoint: 24 hours before the start of aerobic exercise and 24 hours after 12 weeks of exercise. Method of measurement: ELISA kit made by the Chinese company Casabio to measure the amount Transforming growth factor beta 1(TGF-ß1).	—

Measure

Time frame

NT-proBNP concentration. Timepoint: 24 hours before the start of aerobic exercise and 24 hours after 12 weeks of exercise. Method of measurement: ELISA kit made by the Chinese company Casabio to measure the amount of N-terminal pro – B-type natriuretic peptide (NT-proBNP).;CT-1 concentration. Timepoint: 24 hours before the start of aerobic exercise and 24 hours after 12 weeks of exercise. Method of measurement: ELISA kit made by the Chinese company Casabio to measure the amount Cardiotropin-1 ( CT-1).;TGF-ß1 concentration. Timepoint: 24 hours before the start of aerobic exercise and 24 hours after 12 weeks of exercise. Method of measurement: ELISA kit made by the Chinese company Casabio to measure the amount Transforming growth factor beta 1(TGF-ß1).

—

Secondary

Measure	Time frame
Systolic blood pressure. Timepoint: Before and after each workout. Method of measurement: Digital sphygmomanometer in millimeters of mercury.;Diastolic blood pressure. Timepoint: Before and after each workout. Method of measurement: Digital sphygmomanometer in millimeters of mercury.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSomayeh Aabedzadeh

Islamic Azad University

s.abedzade89@gmail.com+98 84 3362 4252

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026