Evaluation the effects of L-carnitin on Cell Blood Indexes in patients on hemodialysis in Sina hospital and Imam Khomeini hospital : A double blinded research(phase 3)

Evaluation the effects of L-carnitin on Cell Blood Indices in patients on hemodialysis in Sina hospital and Imam Khomeini hospital: A double blinded research(phase 3)

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200812048380N2

Enrollment

Registered

2025-07-22

Start date

2025-02-19

Completion date

Unknown

Last updated

2025-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Evaluation the effects of L-carnitine supplementation on blood cell indices in hemodialysis patients.

Interventions

Intervention 1: Intervention group: Intervention group: L-carnitine, 2000 mg/day equivalent to consuming 2 L-carnitine capsules of 1000 mg per day for a period of 60 days made by Karen company. Interv

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: older than 18 y and younger than 65y BMI>20 and <30 kg/m2

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Neutrophil to lymphocyte ratio. Timepoint: At the beginning of the study, one, two and four months later. Method of measurement: CBC.;Platelets to Lymphocyte Ratio. Timepoint: At the beginning of the study, one, two and four months later. Method of measurement: CBC.;Lymphocytes to Monocytes Ratio. Timepoint: At the beginning of the study, one, two and four months later. Method of measurement: CBC.;Mean Platelet Volume. Timepoint: At the beginning of the study, one, two and four months later. Method of measurement: CBC.;Mean Platelet Volume/Platelet Count Ratio. Timepoint: At the beginning of the study, one, two and four months later. Method of measurement: CBC.	—

Measure

Time frame

Neutrophil to lymphocyte ratio. Timepoint: At the beginning of the study, one, two and four months later. Method of measurement: CBC.;Platelets to Lymphocyte Ratio. Timepoint: At the beginning of the study, one, two and four months later. Method of measurement: CBC.;Lymphocytes to Monocytes Ratio. Timepoint: At the beginning of the study, one, two and four months later. Method of measurement: CBC.;Mean Platelet Volume. Timepoint: At the beginning of the study, one, two and four months later. Method of measurement: CBC.;Mean Platelet Volume/Platelet Count Ratio. Timepoint: At the beginning of the study, one, two and four months later. Method of measurement: CBC.

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Secondary

Measure	Time frame
Evaluation of Ferritin Level. Timepoint: At the beginning of the study, one, two and four months later. Method of measurement: Blood sample.;Evaluation of cholesterol levels. Timepoint: At the beginning of the study, one, two and four months later. Method of measurement: Blood sample (Spectrophotometry).;Evaluation of Creatinine concentration. Timepoint: At the beginning of the study, one, two and four months later. Method of measurement: Blood sample (Elisa).;BUN. Timepoint: At the beginning of the study, one, two and four months later. Method of measurement: Blood sample (Elisa).;Evaluation of Uric acid concentration. Timepoint: At the beginning of the study, one, two and four months later. Method of measurement: Blood sample.;Serum Albumin concentration. Timepoint: At the beginning of the study, one, two and four months later. Method of measurement: Blood sample.;C-Reactive Protein. Timepoint: At the beginning of the study, one, two and four months later. Method of measurement: Blood sample.;Assessment of nutritional status Assessment of nutritional status. Timepoint: At the beginning of the study, one, two and four months later. Method of measurement: Anthropometric measurements including weight, height and BMI calculation by dividing weight (kilograms) by the square of height (meters).;Assessment of physical activity status. Timepoint: At the beginning of the study, one, two and four months later. Method of measurement: Short form of International Physical Activity Questionnaire.	—

Measure

Time frame

Evaluation of Ferritin Level. Timepoint: At the beginning of the study, one, two and four months later. Method of measurement: Blood sample.;Evaluation of cholesterol levels. Timepoint: At the beginning of the study, one, two and four months later. Method of measurement: Blood sample (Spectrophotometry).;Evaluation of Creatinine concentration. Timepoint: At the beginning of the study, one, two and four months later. Method of measurement: Blood sample (Elisa).;BUN. Timepoint: At the beginning of the study, one, two and four months later. Method of measurement: Blood sample (Elisa).;Evaluation of Uric acid concentration. Timepoint: At the beginning of the study, one, two and four months later. Method of measurement: Blood sample.;Serum Albumin concentration. Timepoint: At the beginning of the study, one, two and four months later. Method of measurement: Blood sample.;C-Reactive Protein. Timepoint: At the beginning of the study, one, two and four months later. Method of measurement: Blood sample.;Assessment of nutritional status Assessment of nutritional status. Timepoint: At the beginning of the study, one, two and four months later. Method of measurement: Anthropometric measurements including weight, height and BMI calculation by dividing weight (kilograms) by the square of height (meters).;Assessment of physical activity status. Timepoint: At the beginning of the study, one, two and four months later. Method of measurement: Short form of International Physical Activity Questionnaire.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMahshad Ghoddusi

Tehran University of Medical Sciences

mahshad.ghoddusi@gmail.com+98 21 7745 0199

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026