macular amyloidosis. Organ-limited amyloidosis
Conditions
Interventions
Intervention 1: Intervention group: In each patient, the lesion will be randomly divided into 2 zones A and B (two squares of equal size). Zone A under 4 treatment sessions with 4-week intervals of Nd
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Patients with macular amyloidosis clinical symptoms Patients with at least 5 to 10 cm2 macular amyloidosis skin lesion on the trunk or limbs At least 6 months have passed since the onset of skin lesion
Exclusion criteria
Exclusion criteria: Pregnancy, breastfeeding or deciding to get pregnant in the next 2 months Personal history of hypertrophic scar or keloid formation Personal history of melanoma or other skin cancers History of systemic retinoid therapy during last 6 months History of any systemic treatment during the last 3 months for macular amyloidosis history of any topical treatment during the last month for macular amyloidosis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intensity changes of pigmentation. Timepoint: Before the intervention (0) ; 4 weeks after the last session of intervention. Method of measurement: photography with a single camera.;Intensity changes of pigmentation. Timepoint: Before the intervention (0) ; 4 weeks after the last session of intervention. Method of measurement: Questionnaire with Visual Analogue Scale.;Intensity changes of itching. Timepoint: Before the intervention (0) ; 4 weeks after the last session of intervention. Method of measurement: Questionnaire with Visual Analogue Scale. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMaral Yazdanpanah
Esfahan University of Medical Sciences
Outcome results
None listed