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Effect of mytomycin on relapsed nasal polyposis

The effect of topical mitomycin in patients with relapsed nasal polyposis

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200810048356N1
Enrollment
40
Registered
2020-09-29
Start date
2020-07-31
Completion date
Unknown
Last updated
2020-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Recurrence of nasal polyps.

Interventions

Intervention 1: Intervention group: During this trial, at the end of surgery, in one group, cotton mesh impregnated with 1.5 cc of mitomycin 0.1 mg / ml is placing in the nasal cavity for 5 minutes. I

Sponsors

Kashan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
16 Years to 60 Years

Inclusion criteria

Inclusion criteria: Recurrence of nasal polyps after one or more surgery

Exclusion criteria

Exclusion criteria: People with systemic diseases such as diabetes and high blood pressure All patients with underlying disorders including cystic fibrosis, kartagener, respiratory ciliary mobility disorder

Design outcomes

Primary

MeasureTime frame
The symptoms in the two groups of study will be determined and compared before surgery and one and six months after that, as the outcome of this clinical trial by questionnaire. Evaluation of the patient's clinical symptoms in this questionnaire that is based on Rhinosinusitis Symptom Inventory System will be made and scored before and after the treatment. Timepoint: Before surgery and one and six months after that by questionnaire. Method of measurement: Questionnaire based on Rhinosinusitis Symptom Inventory System.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDR Amirhossein Ahsani Arani

Kashan University of Medical Sciences

fatemeh.ffty@gmail.com+98 31 5557 0331

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026