Assessment of Dracocephalum kotschyi in treatment of eczema.

Comparison of anti-inflammatory effect of lotion preparation from hydroalcoholic extract of Dracocephalum kotschyi and clobetasol on patient suffering from eczema.

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200810048352N3

Enrollment

Registered

2024-11-30

Start date

2024-12-21

Completion date

Unknown

Last updated

2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Eczema. Atopic dermatitis, unspecified

Interventions

Intervention 1: Intervention group: Dracocephalum kotschyi lotion (prepared from 10% hydroalcoholic extract in Dr. Shahtalebi production laboratory), will be applied locally twice a day on the affecte

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Men and women 18 years or older. The presence of one or more eczema lesions. Absence of infection or skin malignancy at the treatment site (the presence of a closed wound has no problem). Eczema lesions without exudation. Patients who had not received topical, oral or parental medicine for the treatment of eczema in the last week.

Exclusion criteria

Exclusion criteria: Pregnancy and breast feeding. Patients with other skin lesions Patients who are taking systemic immunosuppressant drugs or biological drugs..

Design outcomes

Primary

Measure	Time frame
Dryness. Timepoint: From the beginning of the study at the end of each week for two weeks. Method of measurement: Pictures of patients before, during and after treatment and Vascorad quality of life questionnaire.;Burning. Timepoint: From the beginning of the study at the end of each week for two weeks. Method of measurement: Pictures of patients before, during and after treatment and Vascorad quality of life questionnaire.;Itching. Timepoint: From the beginning of the study at the end of each week for two weeks. Method of measurement: Pictures of patients before, during and after treatment and Vascorad quality of life questionnaire.;Quality of life. Timepoint: From the start till end of study. Method of measurement: Vascorad quality of life questionnaire.;Redness. Timepoint: From the beginning of the study at the end of each week for two weeks. Method of measurement: Pictures of patients before, during and after treatment and Vascorad quality of life questionnaire.	—

Measure

Time frame

Dryness. Timepoint: From the beginning of the study at the end of each week for two weeks. Method of measurement: Pictures of patients before, during and after treatment and Vascorad quality of life questionnaire.;Burning. Timepoint: From the beginning of the study at the end of each week for two weeks. Method of measurement: Pictures of patients before, during and after treatment and Vascorad quality of life questionnaire.;Itching. Timepoint: From the beginning of the study at the end of each week for two weeks. Method of measurement: Pictures of patients before, during and after treatment and Vascorad quality of life questionnaire.;Quality of life. Timepoint: From the start till end of study. Method of measurement: Vascorad quality of life questionnaire.;Redness. Timepoint: From the beginning of the study at the end of each week for two weeks. Method of measurement: Pictures of patients before, during and after treatment and Vascorad quality of life questionnaire.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactHassan Sadraei

Esfahan University of Medical Sciences

sadraei@pharm.mui.ac.ir+98 31 3792 7086

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026