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The efficacy of Double Ovarian Stimulation for enhancing oocyte yield in assisted reproductive technology in patients with poor ovarian response

Compare the efficacy of two methods of Double Ovarian Stimulation for enhancing oocyte yield in assisted reproductive technology in patients with poor ovarian response

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200804048303N1
Enrollment
34
Registered
2021-07-01
Start date
2021-07-23
Completion date
Unknown
Last updated
2021-07-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

POOR OVERIAN RESPONSE. Ovarian dysfunction, unspecified

Interventions

Intervention 1: Intervention group: In group A, first a course of contraceptive pills was given to patients and then on the first to third day of mensturation ultrasound was done and cinnafact was ad

Sponsors

Shahid Beheshti University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Poor ovarian stimulation based on Poseidon group 3 criteria, AMH less than 1.2 ng / ml, antral follicle count less than 5 and age less than 35 years Group 4 poseidon includes older age equal to 35 years and AMH less than 1.2 ng/ml and the number of antral follicles less than 5 follicles Group 4 poseidon includes older age equal to 35 years and AMH less than 1.2 ng/ml and the number of antral follicles less than 5 follicles

Exclusion criteria

Exclusion criteria: Women with normal or excessive ovarian response Women with excessive ovarian response

Design outcomes

Primary

MeasureTime frame
Number of oocytes. Timepoint: Compare the number of oocytes and MII oocytes after induction ovulation in the follicular and luteal phase and two methods flare stimulation and minimal stimulation,. Method of measurement: Ultrasonography and puncture of oocytes and evaluate the presence of a polar body.;Number of embryos. Timepoint: Number of embryos after induction ovulation and oocyte retrieval in follicular and luteal phase and compare two methods of flare stimulation and minimal stimulation. Method of measurement: Inspection of embryos under the microscope.;Number of blastocysts. Timepoint: The number of blastocysts after oocyte retrieval in the follicular and luteal phases and compare the two methods of flare stimulation and minimal stimulation. Method of measurement: Inspection of embryos under the microscope 5days after oocyte retrieval.

Secondary

MeasureTime frame
Clinical pregnancy. Timepoint: 4-6 weeks after embryo transfer(ET). Method of measurement: Transvaginal ultrasonography and observe existence of gestational sac and fetal heart rate.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSamaneh Sheibani

Shahid Beheshti University of Medical Sciences

Taleghanihospital@sbmu.ac.ir+98 21 2303 1111

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 7, 2026