Cutaneous leishmaniasis. Cutaneous leishmaniasis
Conditions
Interventions
Intervention group: In this group, methylene blue solution (50µL of 0.5% MB in water) is applied topically on the lesion (before prescribing methylene blue, if there is a crust in ulcerative lesions,
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
4 Years to 65 Years
Inclusion criteria
Inclusion criteria: Newly diagnosed localized cutaneous leishmaniasis confirmed by smear Giemsa sample Less than 12 weeks has elapsed since the onset of the lesion No lesion on face Number of lesions is less than four No sporotricoid form Size of lesion is less than 5 centimeters The lesion is not on joints. Urban leishmaniasis (based on patient's clinical observations and regional epidemiology)
Exclusion criteria
Exclusion criteria: Pregnancy and breastfeeding Existence of serious or severe underlying diseases (such as heart disease, kidney disease, liver disease, immunodeficiency)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| UIlcer development and complete lesion epithelialization in ulcerative lesions. Timepoint: Before, during and 12 weeks after the end of treatment. Method of measurement: Clinical observations.;Becoming flat and change in induration diameter in non-ulcerative lesions. Timepoint: Before, during and 12 weeks after the end of treatment. Method of measurement: Clinical observations.;Diameter of induration and erythema and ulcer size. Timepoint: Before, during and 12 weeks after the end of treatment. Method of measurement: Ruler and caliper. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactForough Rakhshanizadeh
Mashhad University of Medical Sciences
Outcome results
None listed