Response of metabolic parameters to 4 weeks of High Intensity Interval Training (HIIT)

Improved fatty liver index- induced high-intensity interval training associated with decrease liver enzyme plasma levels and metabolic parameters in type 2 diabetes

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200729048246N1

Enrollment

Registered

2020-08-21

Start date

2019-05-01

Completion date

Unknown

Last updated

2020-09-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 diabetes. Type 2 diabetes

Interventions

Intervention 1: All of the participants conducted supervised HIIT on cycling ergometer (894E Monark Ergomedic Peak Bike, Varberg, Sweden) three sessions per week for 4- weeks. Each session of HIIT con

Eligibility

Sex/Gender

All

Age

45 Years to 60 Years

Inclusion criteria

Inclusion criteria: Type 2 diabetic patients of Loghman Hakim Hospital A1C more than 6% Lack of Orthopedic diseases Age limit (45 to 60 years) male and female lack of neuromuscular disease lack of Nephropathy lack of Hypertension lack of Myocardial infarction lack of Bypass surgery

Exclusion criteria

Exclusion criteria: Orthopedic diseases neuromuscular disease Nephropathy Hypertension Myocardial infarction Bypass surgery

Design outcomes

Primary

Measure	Time frame
Liver enzyme plasma levels. Timepoint: 24 hours before the intervention period and 48 hours after the intervention period. Method of measurement: ELISA.	—

Secondary

Measure	Time frame
Fatty liver index. Timepoint: 24 hours before the intervention period and 48 hours after the intervention period. Method of measurement: Fatty liver index (FLI) is a non-invasive method for assessing hepatic steatosis which calculated by following formula: FLI= (e 0.953 × loge (triglycerides) + 0.139 × BMI + 0.718 × loge (GGT) + 0.053 × waist circumference – 15.745)/ (1 + e 0.953 × loge (triglycerides) + 0.139 × BMI + 0.718 × loge (GGT) + 0.053 × waist circumference – 15.745) × 100. The FLI was calculated in each subjects.;Lipid profile. Timepoint: 24 hours before the intervention period and 48 hours after the intervention period. Method of measurement: ELISA.;HbA1c. Timepoint: 24 hours before the intervention period and 48 hours after the intervention period. Method of measurement: ELISA.;Renal function, measurement of urea and creatinine. Timepoint: 24 hours before the intervention period and 48 hours after the intervention period. Method of measurement: Quantified by photometry.	—

Measure

Time frame

Fatty liver index. Timepoint: 24 hours before the intervention period and 48 hours after the intervention period. Method of measurement: Fatty liver index (FLI) is a non-invasive method for assessing hepatic steatosis which calculated by following formula: FLI= (e 0.953 × loge (triglycerides) + 0.139 × BMI + 0.718 × loge (GGT) + 0.053 × waist circumference – 15.745)/ (1 + e 0.953 × loge (triglycerides) + 0.139 × BMI + 0.718 × loge (GGT) + 0.053 × waist circumference – 15.745) × 100. The FLI was calculated in each subjects.;Lipid profile. Timepoint: 24 hours before the intervention period and 48 hours after the intervention period. Method of measurement: ELISA.;HbA1c. Timepoint: 24 hours before the intervention period and 48 hours after the intervention period. Method of measurement: ELISA.;Renal function, measurement of urea and creatinine. Timepoint: 24 hours before the intervention period and 48 hours after the intervention period. Method of measurement: Quantified by photometry.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Saeed Kalbasi

Shahid Beheshti University of Medical Sciences

Saeed-Kalbasi@yahoo.com+98 21 5541 9005

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026