Comparison of ketorolac and pethidine in analgesia after orthopedic surgery

Comparison of the effect of ketorolac and pethidine on analgesia and drug use after lower limb orthopedic surgery by spinal anesthesia

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200728048244N1

Enrollment

Registered

2020-08-17

Start date

2020-02-29

Completion date

Unknown

Last updated

2020-09-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain in orthopedic patients. Other acute postprocedural pain

Interventions

Intervention 1: Intervention group1: They receive 30 mg of pethidine intravenously. Intervention 2: Intervention group2:They receive 30 mg of ketorolac intravenously.

Eligibility

Sex/Gender

All

Age

15 Years to 75 Years

Inclusion criteria

Inclusion criteria: Lower limb fractures

Exclusion criteria

Exclusion criteria: History of drug addiction History of migraine Inability to communicate properly with the patient to evaluate postoperative pain Need to be admitted to the ICU after surgery Patients in ASA class 2

Design outcomes

Primary

Measure	Time frame
The pain. Timepoint: After surgery, first in recovery at zero hours, then at 6, 12, 18 and 24 hours after surgery. Method of measurement: pain assessment ruler.	—

Secondary

Measure	Time frame
Vital signs. Timepoint: In minutes 5, 10, 20 and 60, 90 and 120. Method of measurement: monitoring.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSamira Ranjbar

Jahrom University of Medical Sciences

samira.rb24@gmail.com+98 71 2536 5231

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026