Effects of topical drops on the result of tympanoplasty or tympanomastoidectomy surgery

Effects of topical drops on the result of tympanoplasty or tympanomastoidectomy surgery in patients with chronic otitis media at valiasr and Baqiyatallah Hospital in 1392-1393

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200728048241N1

Enrollment

Registered

2020-08-10

Start date

2013-03-21

Completion date

Unknown

Last updated

2020-09-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic otitis media. Other chronic suppurative otitis media

Interventions

Intervention 1: Intervention group: In the intervention group, after removal of dressing, patients received ciprofloxacin eye drop 0.3% 3 to 4 times a day and betamethasone eye drop 0.1% 3 to 4 times

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with chronic otitis media indication for surgery patient preference

Exclusion criteria

Exclusion criteria: Patients with immune deficiency due to diabetes, HIV, oral corticosteroid use History of cholesteatoma Patient rejection History of previous ear surgery

Design outcomes

Primary

Measure	Time frame
Otorrhea due to graft failure. Timepoint: Week 6 and week 12 after surgery. Method of measurement: Examination by microscope.;Tympanic membrane graft success. Timepoint: Week 6 and week 12 after surgery. Method of measurement: Examination by microscope.;Post surgery otitis externa. Timepoint: Week 6 and week 12 after surgery. Method of measurement: Examination by microscope.;Post surgery itching. Timepoint: Week 6 and week 12 after surgery. Method of measurement: Examination by microscope.	—

Measure

Time frame

Otorrhea due to graft failure. Timepoint: Week 6 and week 12 after surgery. Method of measurement: Examination by microscope.;Tympanic membrane graft success. Timepoint: Week 6 and week 12 after surgery. Method of measurement: Examination by microscope.;Post surgery otitis externa. Timepoint: Week 6 and week 12 after surgery. Method of measurement: Examination by microscope.;Post surgery itching. Timepoint: Week 6 and week 12 after surgery. Method of measurement: Examination by microscope.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactSaman Rezaeian

Tehran University of Medical Sciences

s-rezaeian@razi.tums.ac.ir+98 13 3336 6182

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026