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The Effect of Aloe Vera gel, Violet oil and Hydroxyzine on pruritus and dry skin of hemodialysis patients

Comparison of topical effect of Aloe Vera gel and Violet oil with Hydroxyzine for pruritus and dry skin of hemodialysis patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200727048229N1
Enrollment
45
Registered
2021-01-18
Start date
2021-01-04
Completion date
Unknown
Last updated
2021-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Uremic Pruritus. Condition 2: Uremic pruritus. Condition 3: Skin dryness. Condition 4: Dialysis. Condition 5: Chronic kidney disease. Pruritus Pruritus Xerosis cutis Dialysis (renal) Chronic kidney disease (CKD)

Interventions

Intervention 1: In the first group, patients will be treated by 94% of SEAGULL's Aloe Vera gel twice per day for two weeks. Patients will use 3-5 cc of Aloe Vera gel to suit the dry and itchy area. Af

Sponsors

Birjand University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to No maximum

Inclusion criteria

Inclusion criteria: 20 Years and older The cause of dialysis is Chronic Renal Failure. Patients undergoing hemodialysis for at least three months Undergoing hemodialysis at least twice a week history of pruritus for at least 4 weeks The severity of Itching according to the VAS scale is =3. The severity of Dry skin according to VAS scale is =3. Do not use other treatments to relieve Itching and Dry skin during the study including Radiation Therapy, Acupuncture, Complementary Medicine, Topical treatments, Moisturizing. The patient does not attend another Clinical Trial within the next two months. The absence of Pruritic and non-Pruritic skin diseases such as Atopic Dermatitis, Chronic Liver and Biliary disease, HIV, Polycythemia, Skin Eczema, No Inflammatory Skin Lesions, the absence of known allergies (based on Expert doctor's opinion) The absence of Pregnancy and lactation Informed consent

Exclusion criteria

Exclusion criteria: Unwillingness to continue participation in the study for any reason Severe side effects like an allergic reaction to the Aloe Vera gel or Violet oil in patients during the intervention Patient leaving the dialysis center during the study period (due to death, emigration, kidney transplantation). Using other treatments to relieve pruritus during the study including Radiation Therapy, Acupuncture, Complementary Medicine, Topical Treatments Acute disease during the intervention Do not perform interventions for more than one week continuously. According to the researcher's diagnosis, the person is excluded from the study.

Design outcomes

Primary

MeasureTime frame
Dimensions of Pruritus. Timepoint: The day before the intervention and the day after the intervention. Method of measurement: 5-D itch scale.;Intensity of emotions with itching. Timepoint: The day before the intervention and the day after the intervention. Method of measurement: Researcher-made questionnaire (intensity of emotions with itching).;The consequences of itching. Timepoint: The day before the intervention and the day after the intervention. Method of measurement: Researcher-made questionnaire (The consequences of itching).;The severity of itching. Timepoint: The day before the intervention and the day after the intervention. Method of measurement: Visual Analogue Scale (VAS).;The severity of dry skin. Timepoint: The day before the intervention and the day after the intervention. Method of measurement: Visual Analogue Scale (VAS).

Secondary

MeasureTime frame
Quality of life. Timepoint: at weeks 0 and 8. Method of measurement: Dermatology Life Quality Iindex (DLQI).;Satisfaction rate of each intervention. Timepoint: The day after the end of each intervention. Method of measurement: Visual Analogue Scale (VAS).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNima- RezaAliZadeh

Birjand University of Medical Sciences

nimarezaaliazdeh@gmail.com+98 13 4486 1278

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026