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Comparison of the effect of Olapatadine nasal spray with Mometasone spray in the treatment of allergic rhinosinusitis

Evaluation of the effect of Olopatadine nasal spray compared to Mometasone spray in the treatment of allergic rhinosinusitis cases refered to ENT clinic of Heshmatieh Hospital Sabzevar

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200727048222N1
Enrollment
100
Registered
2020-09-26
Start date
2020-08-21
Completion date
Unknown
Last updated
2020-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Allergic rhinosinusitis. Allergic rhinosinusitis

Interventions

Intervention 1: Intervention group: Olopatadine nasal spray 0.6% every 12 hours (made by Daroo Pakhsh Tehran). Intervention 2: Intervention group: Mometasone 50 mg nasal spray every 6 hours (made by C

Sponsors

Sabzevar University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Age 18 to 60 years Patients with confirmed allergic rhinosinusitis Written consent to enter the study Patient cooperation during the study Timely and correct use of medication by asking the patient Absence of abnormal nasal anatomy Absence of severe nasal congestion due to polyps, other lesions and obstructive masses Absence of respiratory infections Non-smokers Absence of upper and lower lung diseases affecting the final consumption or absorption of the nose Absence of symptoms of systemic diseases

Exclusion criteria

Exclusion criteria: People known for not responding to antihistamines Known intolerance or sensitivity to drugs

Design outcomes

Primary

MeasureTime frame
Response to treatment of olapatadine and mometasone spray groups. Timepoint: Before the intervention and on days 1, 3 and week 2 after starting the medication. Method of measurement: Sino Nasal Outcome Test 22 questionnaire.;Satisfaction of patients receiving olapatadine and mometasone spray groups. Timepoint: 2 weeks After starting the intervention. Method of measurement: 5 point scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactEhsan Ebrahimzadeh

Sabzevar University of Medical Sciences

ehsanebrahimzadeh@yahoo.com+98 51 4424 3658

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026