Evaluation of the effect of phenylephrine in cesarean section

Evaluation of the comparative effect of hemodynamic changes due to prophylactic Prescription of phenylephrine in three forms: bolus, subcutaneous and infusion in mothers with selective cesarean section under spinal anesthesia with marcaine

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200725048206N1

Enrollment

120

Registered

2020-08-20

Start date

2020-07-31

Completion date

Unknown

Last updated

2020-09-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hemodynamics of pregnant women under spinal anesthesia.

Interventions

Intervention 1: Intervention group 1: Bolus method: For patients who are going to receive bolus prophylactic phenylephrine (Beacon Pharmaceuticals Ltd) , 1.5 µ g / kg of phenylephrine is injected 1 to

Eligibility

Sex/Gender

Female

Age

18 Years to 35 Years

Inclusion criteria

Inclusion criteria: Pregnant women Term Single pregnancy Elective cesarean section candidate

Exclusion criteria

Exclusion criteria: History of hypertension (BP> 140/90 Diabetes Cardiovascular and cerebral disease Recognized fetal anomaly Any contraindication to spinal anesthesia Mothers who are at the beginning of the labor phase

Design outcomes

Primary

Measure	Time frame
Blood pressure. Timepoint: Base and minutes 5 and 15 and 30 and 60 and 90 and 120. Method of measurement: Cardiac monitor machine and blood pressure meter.;Heart rate. Timepoint: Base and minutes 5 and 15 and 30 and 60 and 90 and 120. Method of measurement: Cardiac monitor machine and pulse oximeter.;Apgar score. Timepoint: Minutes 1 and 5. Method of measurement: Physical examination.;Umbilical cord blood Paco2 test. Timepoint: After birth. Method of measurement: Laboratory instruments.;Umbilical cord blood HCO3 test. Timepoint: After birth. Method of measurement: Laboratory instruments.;Umbilical cord blood pH test. Timepoint: After birth. Method of measurement: Laboratory instruments.;Umbilical cord blood Base excess test. Timepoint: After birth. Method of measurement: Laboratory instruments.	—

Measure

Time frame

Blood pressure. Timepoint: Base and minutes 5 and 15 and 30 and 60 and 90 and 120. Method of measurement: Cardiac monitor machine and blood pressure meter.;Heart rate. Timepoint: Base and minutes 5 and 15 and 30 and 60 and 90 and 120. Method of measurement: Cardiac monitor machine and pulse oximeter.;Apgar score. Timepoint: Minutes 1 and 5. Method of measurement: Physical examination.;Umbilical cord blood Paco2 test. Timepoint: After birth. Method of measurement: Laboratory instruments.;Umbilical cord blood HCO3 test. Timepoint: After birth. Method of measurement: Laboratory instruments.;Umbilical cord blood pH test. Timepoint: After birth. Method of measurement: Laboratory instruments.;Umbilical cord blood Base excess test. Timepoint: After birth. Method of measurement: Laboratory instruments.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMajid Aftabi

Ilam University of Medical Sciences

majidaftabi73@gmail.com+98 84 3222 1999

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026