Skip to content

Preparation of herbal cream from extract of Scrophularia striata, Achillea millefolium, Allium jesdianum for the treatment of bacterial vaginitis

Preparation of herbal cream from the hydroalcoholic extract of Scrophularia striata, Achillea millefolium, Allium jesdianum for the treatment of bacterial vaginitis in married women over 18 years of age: a three-blind randomized clinical trial study

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200721048159N10
Enrollment
120
Registered
2026-05-14
Start date
2026-06-22
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bacterial vaginitis. Acute vaginitis

Interventions

Intervention 1: Intervention group: Intervention group:They uses 0/75% metronidazol vaginal gel along with vaginal cream containing 5% hydroalcoholic extract of the Scrophularia Striata, Achillea mill

Sponsors

Khoram-Abad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Women in the age range of 18 to 45 years Being married Having at least 3 of the 4 amsel criteria Having informed consent BMI less than 30

Exclusion criteria

Exclusion criteria: BMI less than 30 presence if other vaginitis along with bacterial vaginitis The patients lack of consent to continue participating in the study Abnormal vaginal bleeding Pregnancy Other systemic diseases History of smoking, drugs or alcohol Use of cryothetapy during the six weeks before the study History of frequent infections (4 or more than 4 times a year) History of allergy to medicinal herbs and metronidazol Using antibiotics in the last two weeks Using vaginal creams, suppositories or shower in the last 48 hours Atrophic vaginitis Hormonal disorders Using Hormonal medications Using probiotics

Design outcomes

Primary

MeasureTime frame
Evaluation of Amsels clinical criteria. Timepoint: Evaluation of clinical symptoms based on the Amsels criteria at the beginning of the study and 2 to 7 days after the end of the treatment period. Method of measurement: Patient examination and sampling.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactForouzan Ahmadpour

Khoram-Abad University of Medical Sciences

ahmadpourforoz@yahoo.com+98 66 3312 0239

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Jun 11, 2026