Oral mucositis due to antineoplastic therapy. Oral mucositis (ulcerative) due to antineoplastic therapy
Conditions
Interventions
Intervention 1: Intervention group: Intervention group Herbal mouthwash containing 6.25% hydroalcoholic extract of pomegranate peel and 0.1% hydroalcoholic extract of turmeric, once every 6 hours, 30
Sponsors
Khoram-Abad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Patients in the age range of 18 to 65 years Cancer patients with chemotherapy-induced oral inflammation Patients are able to complete a questionnaire and collaborate with the researcher Absence of serious dental problems or teeth damaging the oral mucosa or sharp fillings Do not use dentures Do not use anti-inflammatory and other mouthwash solutions during research No other systemic diseases No history of smoking, drugs and alcohol No oral candidiasis (fungus) or herpes simplex (virus) Do not use cryotherapy for six weeks before the study
Exclusion criteria
Exclusion criteria: Dissatisfaction with participating in the study Participate in another clinical trial at the same time History of allergies to turmeric and pomegranate, lidocaine, antacids, diphenhydramine and dexamethasone Inability of the patient to implement the treatment protocol Patient death due to failure to respond to anticancer therapy Combination therapies such as radiation therapy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Grade of mucositis based on WHO scale. Timepoint: Evaluation of grade of mucositis at the beginning of the study, 7 and 14 days after mouthwash containing pomegranate and turmeric extract. Method of measurement: Standard questionnaire and patient examination. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactForouzan Ahmadpour
Khoram-Abad University of Medical Sciences
Outcome results
None listed