The effect of low-dose hydrocortisone on neonatal respiratory status under mechanical ventilation

Investigation of the effect of low-dose hydrocortisone on neonatal respiratory status under mechanical ventilation

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200721048155N1

Enrollment

Registered

2020-08-01

Start date

2020-02-05

Completion date

Unknown

Last updated

2020-08-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

respiratory status under mechanical ventilation. Other chronic respiratory diseases originating in the perinatal period

Interventions

Intervention 1: Intervention group: In this group, Intravenous dexamethasone 24 hours before until 48 hours after extubation with the dose of 0.5 mg/kg /day will be administered. In addition, hydrocor

Eligibility

Sex/Gender

All

Age

7 Days to 30 Days

Inclusion criteria

Inclusion criteria: Preterm neonates who have been under mechanical ventilation for at least 14 days Informed consent of the patient's legal guardian

Exclusion criteria

Exclusion criteria: Heart patients with failure Observable irregularities Neuromuscular diseases which influence respiratory effort

Design outcomes

Primary

Measure	Time frame
Status of need for mechanical ventilation based on level of oxygen needed. Timepoint: Before and during intervention and after disconnection from ventilation. Method of measurement: Patient monitoring device.;Duration of connection to the ventilation device. Timepoint: Before intervention. Method of measurement: Counting the number of days patient was connected to the ventilation device.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactRaheleh Faramarzi Garmroudi

Mashhad University of Medical Sciences

faramarzigr@mums.ac.ir+98 51 3801 2496

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026