Alzheimer's disease. Alzheimer's disease
Conditions
Interventions
Intervention 1: Intervention group: Patients with confirmed Alzheimer's disease were randomly selected and receive 3 capsules containing lavender extract daily. Extraction is prepared by hydro-alcoho
Sponsors
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
60 Years to No maximum
Inclusion criteria
Inclusion criteria: Alzheimer's patients in stage 1 and 2, whose diagnosis of Alzheimer's disease is based on ICD10 / DSM-IV criteria. These criteria include: 1- Multiple cognitive deficits that include memory impairment and at least one of the signs of aphasia, apraxia, agnosia and executive dysfunction, 2- Existence of cognitive deficits severe enough to cause occupational and social dysfunction and show Provides a reduction in the previous performance level.
Exclusion criteria
Exclusion criteria: End-stage patients of Alzheimer's disease According to ICD10 / DSM-IV criteria, patient with a cognitive impairment is excluded from the study if dementia is not diagnosed in the delirium period. Patients with cognitive deficits are due to other central nervous system diseases such as Parkinson's, or systemic diseases such as hypothyroidism and substance abuse.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mini–Mental State Examination (MMSE) score. Timepoint: At the beginning of the study and after one month of intervention. Method of measurement: Mini–Mental State Examination.;Alteration of blood metabolites. Timepoint: Before the intervention and one month after the intervention. Method of measurement: Nuclear magnetic resonance (NMR) device.;Altered urinary metabolites. Timepoint: Before the intervention and one month after the intervention. Method of measurement: Nuclear magnetic resonance (NMR)device. | — |
Secondary
| Measure | Time frame |
|---|---|
| Awareness of time. Timepoint: Before the intervention and one month after the intervention. Method of measurement: With MMSE test score.;Awareness of location. Timepoint: Before the intervention and after a month. Method of measurement: With MMSE test score.;Memory. Timepoint: Before the intervention and after a month. Method of measurement: With MMSE test score.;Attention and calculation. Timepoint: Before the intervention and after a month. Method of measurement: With MMSE test score. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public Contacthakimeh zali
Shahid Beheshti University of Medical Sciences
Outcome results
None listed