Evaluation of the effectiveness of black seed oil in the treatment of vulvovaginal mucositis

Evaluation of the effectiveness of topical application of special emulsion for epithelial tissue prepared with black seed oil in the treatment of vulvovaginal mucositis

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200720048145N2

Enrollment

100

Registered

2020-09-07

Start date

2020-09-19

Completion date

Unknown

Last updated

2020-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Inflammation of the vulvovaginal mucosa. Vaginitis, vulvitis and vulvovaginitis in diseases classified elsewhere

Interventions

Intervention 1: Intervention group: Patients use topical spray made from black seed oil emulsion at a dose of 1% twice a day at a dose of 2 puffs for 7 days. Intervention 2: Intervention group: Patie

Eligibility

Sex/Gender

Female

Age

15 Years to 60 Years

Inclusion criteria

Inclusion criteria: Age 15-60 years Do not using immunosuppressive drugs, antibiotics and topical creams and ointments during the last week Do not be pregnant or breastfeeding Normal Pap smear test

Exclusion criteria

Exclusion criteria: Allergy to the drug prescribed to the patient Failure to follow treatment regularly and as directed Mandatory administration of antibiotics by another physician outside the scope of the present study Having sex with multiple partners during treatment

Design outcomes

Primary

Measure	Time frame
Inflammation of the vagina. Timepoint: In two stages before the intervention and after the intervention. Method of measurement: Examination of the vagina.	—

Secondary

Measure	Time frame
Vaginal discharge. Timepoint: Before and 7 days after the start of the intervention. Method of measurement: Questionnaire.;Vaginal itching. Timepoint: Before and 7 days after the start of the intervention. Method of measurement: Questionnaire.;Bad smell of vaginal discharge. Timepoint: Before and 7 days after the start of the intervention. Method of measurement: Questionnaire.;Vaginal burning. Timepoint: Before and 7 days after the start of the intervention. Method of measurement: Questionnaire.;Painful intercourse. Timepoint: Before and 7 days after the start of the intervention. Method of measurement: Questionnaire.;Urinary incontinence. Timepoint: Before and 7 days after the start of the intervention. Method of measurement: ????????.	—

Measure

Time frame

Vaginal discharge. Timepoint: Before and 7 days after the start of the intervention. Method of measurement: Questionnaire.;Vaginal itching. Timepoint: Before and 7 days after the start of the intervention. Method of measurement: Questionnaire.;Bad smell of vaginal discharge. Timepoint: Before and 7 days after the start of the intervention. Method of measurement: Questionnaire.;Vaginal burning. Timepoint: Before and 7 days after the start of the intervention. Method of measurement: Questionnaire.;Painful intercourse. Timepoint: Before and 7 days after the start of the intervention. Method of measurement: Questionnaire.;Urinary incontinence. Timepoint: Before and 7 days after the start of the intervention. Method of measurement: ????????.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Reza Maghsoudi

Alborz University of Medical Sciences

dr.maghsoudi@abzums.ac.ir+98 26 3252 7576

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026