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Effect of Varenicline in smoking cessation after invasive treatment of coronary artery disease

?Efficacy of Varenicline for smoking cessation among persistent smokers after coronary artery revascularization: A randomized placebo controlled clinical trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200719048133N1
Enrollment
600
Registered
2020-07-23
Start date
2020-08-22
Completion date
Unknown
Last updated
2020-08-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Smoking cessation.

Interventions

Intervention 1: Intervention group: Patients in this arm will be instructed to use Varenicline based on the following protocol: A 0.5 mg tablet once daily for 3 days, A 0.5 mg tablet twice daily for 4

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Male sex = 18 years old Current daily smoker of = 5 cigarettes per day Having a history of revascularization procedure for CAD in Tehran Heart 9-12 months prior to the study Able to consent to the study and to follow its instructions and procedures

Exclusion criteria

Exclusion criteria: Unstable cardiac disease Known case of dementia disorders such as Alzheimer Known case of chronic renal failure Known or suspected unstable psychiatric disorders that require acute medical treatment Only one member of a household is permitted to participate in the trial concurrently to minimize cohort-confounding effects

Design outcomes

Primary

MeasureTime frame
Group differences in the continuous abstinence rate. Timepoint: Point prevalence abstinence at the end of 13 and 52 weeks of intervention. Method of measurement: Self-reported rating scales that is confirmed by one of the close relatives who lives with patient.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMasoumeh Lotfi Tokaldany

Tehran University of Medical Sciences

lotfi21366@yahoo.co.uk+98 21 8802 9256

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026