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Evaluation of the effectiveness of Hydroxychloroquine and Clarithromycin in dyspnea and caugh caused by COVID-19 in recovery phase

Evaluation and comparison of the effectiveness of Hydroxychloroquin versus Clarithromycin in recovery of dyspnea and Caugh at the end of the acute phase of COVID-19 treatment

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200718048129N1
Enrollment
45
Registered
2020-08-11
Start date
2020-08-22
Completion date
Unknown
Last updated
2020-09-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COVID-19. COVID19 ,virus identified

Interventions

Intervention 1: Intervention group 1: Hydroxychloroquine tablets 200 mg every 12 hours for one month fram Rooz daroo company. Intervention 2: Intervention group 2: Clarithromycin 500 mg capsules ever

Sponsors

Iran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 50 Years

Inclusion criteria

Inclusion criteria: Patients with definitive diagnosis of COVID19 were hospitalized and treated Patients with COVID19 who still have dyspena and cough two weeks after discharge from the hospital Patients with COVID19 who continue to have lung involvement on CT SCAN two weeks after discharge

Exclusion criteria

Exclusion criteria: Patients with comorbidities such as chronic heart or lung disease before COVID19 The need for long-term use of drugs that have an irreversible interaction with the drugs used in the plan.

Design outcomes

Primary

MeasureTime frame
Dyspnea. Timepoint: Beginning of the study (before the intervention), 14, 30 days after the start of the study. Method of measurement: Medical Research Council(MRC).;Cough. Timepoint: Beginning of the study (before the intervention), 14, 30 days after the start of the study. Method of measurement: visual analogue scale(vas).

Secondary

MeasureTime frame
Lung function. Timepoint: At the beginning of the study (before the intervention) and 30 days later at the end of the study. Method of measurement: six minute walk test(6MW).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSima Bahrami

Iran University of Medical Sciences

bahrami.s@iums.ac.ir+98 21 6435 1000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026