Effect of Topical Mycophenolate, Zinc and Aloe vera in oral lichen planus ulcers

Effect of injectable mucoadhesive polymeric scaffolds containing aloe vera gel,zinc and mycophenolate mofetil on oral lichen planus lesions

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200708048057N1

Enrollment

Registered

2020-09-04

Start date

2020-01-21

Completion date

Unknown

Last updated

2020-09-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oral lichen planus. oral lichen planus

Interventions

Intervention 1: Intervention group:The case lesion will be covered by scaffolds containing aloe vera extract, zinc and mycophenolate mofetil. Intervention 2: Control group: The control lesion will be

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age over 18 years A patient who is diagnosed with lichen planus on pathological examination. Willingness to participate in the study Existence of a bilateral lesion

Exclusion criteria

Exclusion criteria: Pregnant and lactating women Systemic use of corticosteroids High blood pressure Smokers All items where topical corticosteroids are contraindicated, such as: uncontrolled diabetes, history of tuberculosis, gastric ulcer Adjacent waste with amalgam filling Systemic diseases

Design outcomes

Primary

Measure	Time frame
Size of erythema and ulcer. Timepoint: 15 days after treatment. Method of measurement: dental micrometer (colis) .	—

Secondary

Measure	Time frame
Pain and burning. Timepoint: 15 days after receiving the drug. Method of measurement: visual analog scale (VAS).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZahra Aghazadeh

Tabriz University of Medical Sciences

Maghazadehbio@gmail.com+98 41 3328 3639

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026