Evaluation of the effects of intranasal desmopressin on intraoperative blood loss and quality of the surgical field during open rhinoplasty

Clinical Trial of Evaluation of the effects of intranasal desmopressin on intraoperative blood loss and quality of the surgical field during open rhinoplasty:

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200708048051N3

Enrollment

120

Registered

2021-02-20

Start date

2021-02-19

Completion date

Unknown

Last updated

2021-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rhinoplasty surgery.

Interventions

Intervention 1: Intervention group 1: Topical desmopressin spray inside the nose, one puff in each nostril (equivalent to 20 micrograms) one hour before surgery. Intervention 2: Intervention group 2:

Eligibility

Sex/Gender

All

Age

18 Years to 40 Years

Inclusion criteria

Inclusion criteria: All patients 18 to 40 years old who are candidates for rhinoplasty

Exclusion criteria

Exclusion criteria: People with abnormal coagulation tests People with a history of cardiovascular disease Patients with coagulation diseases People taking anticoagulants Patients with brain diseases, hypertension and diabetes Pregnant women History of seizures Consumption of herbal supplements and vitamin E. Corticosteroid users in the last two weeks Consumers of diuretics Vulnerable groups History of previous rhinoplasty

Design outcomes

Primary

Measure	Time frame
Quality of the surgical field during surgery. Timepoint: During the operation. Method of measurement: The quality of the surgical field is determined by the surgeon during the operation based on the BOEZAART criteria.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaliheh Akbarpour

Rasht University of Medical Sciences

Akbarpour@gums.ac.ir+98 13 2333 8308

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026