Idiopathic Sudden Sensorineural Hearing Loss. Sudden idiopathic hearing loss, unspecified ear
Conditions
Interventions
Intervention 1: Intervention group: Prednisolone (Nisopred ®, Iranhormone Co.) tablets at a dose of 1 mg / kg daily (maximum 60 mg as a single dose in the morning) for 10 days and then taper for 5 day
Sponsors
Rasht University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Patients with a unilateral sudden sensory hearing loss Refer to the hospital in less than 5 days from the onset of symptoms Hearing loss of = 30 dB at least 3 consecutive frequencies in the audiometery.
Exclusion criteria
Exclusion criteria: Patients with a history of hearing loss, trauma to the ear, active ear infection, congenital cochlear disease Use of ototoxic drugs, anticoagulants, anticonvulsants. Cardiovascular disease, coagulation disorders, and diabetes. Retro cochlear lesions Severe renal and hepatic impairment (Cr clearance less than 15) People with neoplasms who have not been treated or are being treated with chemotherapy or radiotherapy. pregnancy and breastfeeding Patients with history of autoimmune disorder Patients with platelet count disorder (less than 150,000)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hearing threshold. Timepoint: Before starting treatment and 2 weeks after and 3 months after starting treatment. Method of measurement: Pure tone audiometry. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Mir Mohammad Jalali
Rasht University of Medical Sciences
Outcome results
None listed