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The effect of Portulaca oleracea syrup on mild to moderate chronic hand dermatitis

Evaluation of the efficacy and safety of Purslane (Portulaca oleracea) Product on Clinical Symptoms of Mild to Moderate Chronic Hand Dermatitis

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200707048040N1
Enrollment
70
Registered
2020-08-08
Start date
2020-08-20
Completion date
Unknown
Last updated
2020-08-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

mild to moderate chronic dermatitis. Dermatitis, unspecified

Interventions

Intervention 1: Intervention group: Intervention group: Recipient of Portulaca oleracea syrup (25 mg/ ml) 10 cc three times a day for 4 weeks orally prepared to contain aqueous extract of Portulaca ol

Sponsors

Shahid Beheshti University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Patients with chronic unilateral or bilateral hand dermatitis, including occupational dermatitis, allergic dermatitis or irritative dermatitis Age range 18 to 70 years Willingness and satisfaction to participate in the study Referred to traditional medicine center

Exclusion criteria

Exclusion criteria: Breastfeeding Pregnancy Patients with severe dermatitis Patients with underlying diseases such as cardiovascular failure, diabetes, immune deficiency, autoimmune diseases, spinal cord diseases Patients taking medication for their other illnesses Patients who develop another acute illness during treatment Patients who have an infection at the site of their dermatitis Patients who are allergic to Portulaca oleracea

Design outcomes

Primary

MeasureTime frame
Erythema. Timepoint: Week zero, the end of the fourth and eighth weeks. Method of measurement: HECSI Scale.;Edema. Timepoint: Week zero, the end of the fourth and eighth weeks. Method of measurement: HECSI Scale.;Fissure. Timepoint: Week zero, the end of the fourth and eighth weeks. Method of measurement: HECSI Scale.;Scaling. Timepoint: Week zero, the end of the fourth and eighth weeks. Method of measurement: HECSI Scale.;Itching. Timepoint: Week zero, the end of the second, fourth and eighth weeks. Method of measurement: VAS Scale.;Dryness. Timepoint: Week zero, the end of the second, fourth and eighth weeks. Method of measurement: VAS Scale.;Skin thickness. Timepoint: Week zero, the end of the second, fourth and eighth weeks. Method of measurement: VAS Scale.;Drug side effects. Timepoint: Week zero, the end of the second, fourth and eighth weeks. Method of measurement: Question from the patient.

Secondary

MeasureTime frame
Dermatology life quality index. Timepoint: Week zero, the end of the fourth and eighth weeks. Method of measurement: DLQI questionnair.;Patients' overall satisfaction with treatment. Timepoint: End of the fourth week. Method of measurement: Likert Scale.;Recurrence of symptoms after treatment. Timepoint: the end of the eighth week. Method of measurement: Question from the patient.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSedigheh Rastegar

Shahid Beheshti University of Medical Sciences

rastegar.sedigheh54@sbmu.ac.ir+98 21 8877 3521

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 10, 2026