H pylori infection. Helicobacter pylori [H. pylori] as the cause of diseases classified elsewhere
Conditions
Interventions
Intervention 1: Intervention group: four-agents-based on levofloxacin-tetracycline-group A.Tetracycline-levofloxacin group regimen includes: tetracycline 500 mg every 12 hours, levofloxacin 500 mg dai
Sponsors
Ahvaz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: selection of patients based on clinical complaint of non-ulcer dyspepsia and endoscopy (confirmation of peptic ulcer or pathological confirmation of intestinal metaplasia or gastritis in the field of H. pylori) with a positive RUT test no previous treatment for H. pylori infection no use of quinolone and macrolide antibiotics during the last two months. over 18 years of age.
Exclusion criteria
Exclusion criteria: Severe side effects of the drug that lead to discontinuation of the drug before completing one week of treatment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Percentage of people with non-ulcer dyspepsia. Timepoint: at initiation of study. Method of measurement: performing upper gastrointestinal endoscopy.;Percentage of people with intestinal metaplasia. Timepoint: at initiation of study. Method of measurement: performing upper gastrointestinal endoscopy.;Percentage of people with peptic ulcer disease. Timepoint: at initiation of study. Method of measurement: performing upper gastrointestinal endoscopy. | — |
Secondary
| Measure | Time frame |
|---|---|
| H-pylori eradication. Timepoint: after completing treatment. Method of measurement: Stool antigen test for H-pylori.;Drug side effect. Timepoint: every week. Method of measurement: according to patient. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactTahmineh Farbod Ara
Ahvaz University of Medical Sciences
Outcome results
None listed