The effect of Alpinia galanga oil on reducing the symptoms of knee osteoarthritis

Comparing the effect of topical application of Alpinia galanga (Qost) Oil and Diclofenac jel on symptoms of knee osteoarthritis

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200701047978N1

Enrollment

158

Registered

2020-08-16

Start date

2020-08-04

Completion date

Unknown

Last updated

2020-09-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee Osteoarthritis. Osteoarthritis of knee

Interventions

Intervention 1: Intervention group: Alpinia galanga Oil 5 to 10 drops (amount of active ingredient equal to 80% in sesame oil base made by Tehran School of Pharmacy), twice a day for 28 days topically

Eligibility

Sex/Gender

All

Age

45 Years to 70 Years

Inclusion criteria

Inclusion criteria: Age of 45 to 70 years old Patients with osteoarthritis according to the American College of Rheumatology Criteria and grade 1 to 3 osteoarthritis according to the Clagren-Lawrence criterion Written consent to enter the study Patient cooperation during the study Possibility of timely and correct use of medicine

Exclusion criteria

Exclusion criteria: Patients with abnormal knee anatomy and joint replacement surgery Patients with knee joint infections Suffering from serious underlying diseases such as liver and kidney disorders, diabetes, etc. Patients with severe skin problems of the knee area Patients with intra-articular injection of steroids within the last three months prior to enrollment Patients with intramuscular steroid injections within the past month before enrollment Patients with known intolerance or allergy to Diclofenac or Alpinia Galanga Blindness and deafness or inability to communicate Taking psychotropic drugs Taking drugs or taking corticosteroids

Design outcomes

Primary

Measure	Time frame
Joint dryness. Timepoint: Before the intervention, after 14 and 28 days after the use of Alpinia galanga Oil and diclofenac gel. Method of measurement: WOMAC standard questionnaire.;Pain. Timepoint: Before the intervention, after 14 and 28 days after the use of Alpinia galanga Oil and diclofenac gel. Method of measurement: WOMAC standard questionnaire.;Physical function. Timepoint: Before the intervention, after 14 and 28 days after the use of Alpinia galanga Oil and diclofenac gel. Method of measurement: WOMAC standard questionnaire.	—

Measure

Time frame

Joint dryness. Timepoint: Before the intervention, after 14 and 28 days after the use of Alpinia galanga Oil and diclofenac gel. Method of measurement: WOMAC standard questionnaire.;Pain. Timepoint: Before the intervention, after 14 and 28 days after the use of Alpinia galanga Oil and diclofenac gel. Method of measurement: WOMAC standard questionnaire.;Physical function. Timepoint: Before the intervention, after 14 and 28 days after the use of Alpinia galanga Oil and diclofenac gel. Method of measurement: WOMAC standard questionnaire.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactFereshteh Ghorat

Sabzevar University of Medical Sciences

drghorat@gmail.com+98 51 4401 1000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026