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Effects of Betamethasone In Total Knee Arthroplasty

Evaluating The Results Of Addition Of Betamethasone To Multimodal Cocktail Periarticular Injection In Bilateral Total Knee Arthroplasty

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200627047934N1
Enrollment
30
Registered
2020-07-07
Start date
2018-12-05
Completion date
Unknown
Last updated
2020-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bilateral osteoarthritis of knee. Bilateral primary osteoarthritis of knee

Interventions

Intervention 1: We divide patients by randomization with 4 blocks into groups A and B. Group A includes patients who are injected with a cocktail containing betamethasone in their right leg. In group

Sponsors

Islamic Azad University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 90 Years

Inclusion criteria

Inclusion criteria: People aged 50 to 90 years Having advanced osteoarthritis of both knees

Exclusion criteria

Exclusion criteria: People who did not agree to study and use their information Contraindications to the use of the studied drugs (including known allergies or intolerance to one of the drugs, fungal infections, having heart, liver, brain, kidney disease and inflammatory diseases of the joints, people with bleeding disorders, gastrointestinal bleeding, Asthma, glaucoma, cataracts and diabetic patients) Patients weighing more than 100 kg Patients with neuropathic pain and sensory disturbances in the foot Patients with a history of knee surgery

Design outcomes

Primary

MeasureTime frame
Pain score. Timepoint: It is measured at hours 6, 18, 24, 48 and on days 7, 14 and 60 after surgery. Method of measurement: Visual Analogue Scale.;Knee range of motion. Timepoint: It will be measured at 24, 48 hours and 7 and 60 days after surgery. Method of measurement: Gonia meters.;Oxford Knee Score. Timepoint: It will be checked before the operation and on the 60th day after the operation. Method of measurement: questionnaire.;Wound complications. Timepoint: At any time of the visit. Method of measurement: Observation and examination.

Secondary

MeasureTime frame
Patients' satisfaction with pain control. Timepoint: It will be asked at hours 24, 48 and on days 7 and 60 after the operation. Method of measurement: questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFarivar Bagheri

Islamic Azad University

Dr.mamad73@gmail.com+98 23 3239 2661

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026