Breast Cancer. Malignant neoplasm of breast
Conditions
Interventions
Intervention group: Metastatic Breast cancer patients with no response to treatment who received a conditioning regimen and two dosages of immune cell infusion a week apart (1-10x10^6 cells/Kg). Natur
Sponsors
Motamed Cancer Institute
Modiriat Atiyeh Bahman Company
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Breast cancer diagnosed with pathological report Approved according to Recist form for metastatic breast cancer [EF=50%]EJECTION FRACTION ElectroCochleoGraphy (ECoG) =0-1 ANC=1500, PH=100,000, GFR=60, T.Bil=1.5xULN, AST, ALT=2xULN bHCG=negative Ability to fill out a consent form and agree to its terms PS=0-1
Exclusion criteria
Exclusion criteria: Receiving any anticancer drug at the same time Major surgery one month before enrollment An active infection that impairs a patient's tolerance for treatment Breastfeeding or pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Symptoms of Hypersensitivity. Timepoint: Every day after infusion until to 1 week and weekly until to 3 months. Method of measurement: Physical examination and MRI-CT.;Tumor size. Timepoint: Every months until to 3 months. Method of measurement: Physical examination- Lab diagnostic tests- MRI-ST scan.;Symptoms of GVHD. Timepoint: Every day after infusion until to 1 week and weekly until to 3 months. Method of measurement: Physical examination- Lab diagnostic tests- MRI-ST scan.;Metastasis. Timepoint: Monthly until to 3 months. Method of measurement: Physical examination- Lab diagnostic tests- MRI-ST scan. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Ramin Sarrami Forooshani
Iranian academic center for education culture and research
Outcome results
None listed