Type 2 diabetes with vitamin D deficiency.
Conditions
Interventions
Intervention group: Vitamin D tablets (1 and 25 hydroxyvitamin D3), every week for 8 weeks at a dose of 50,000 units, a product of Zahravi Pharmaceutical Company (Tabriz).
Sponsors
Birjand University of Medical Sciences
Eligibility
Sex/Gender
All
Age
50 Years to 65 Years
Inclusion criteria
Inclusion criteria: The disease (diabetes) has already been confirmed by a specialist. People with diabetes who have had diabetes for at least 5 years The criterion for entering the diabetic group is HbA1C, which is outside the normal range. Age range 50-65 years The desire to participate in the study
Exclusion criteria
Exclusion criteria: Systemic diseases (rheumatoid arthritis ...) that can affect the results. Cancer Taking corticosteroids Thyroid disease Kidney diseases and adrenal glands Liver diseases Multivitamin consumption
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Vitamin D levels. Timepoint: First and after 8 weeks. Method of measurement: Vitamin D will be measured with a little luminescence technique. | — |
Secondary
| Measure | Time frame |
|---|---|
| HDL, LDL, A1C hemoglobin levels, Nlrp3 gene, and oxidative stress status. Timepoint: First and after 8 weeks. Method of measurement: Tests (LDL, HDL) are performed with kits and enzymatic methods. The A1C Hb will be measured using the immunomturbidometry technique. However, PCR real-time techniques are used for genetic testing, as well as tests for oxidative stress status with TAC antioxidant kits by FRAP, Thiol group, and MDA by spectrophotometry. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactShadi
Birjand University of Medical Sciences
Outcome results
None listed