Condition 1: dry eye. Condition 2: Vitamin D deficiency. Other disorders of lacrimal gland Vitamin D deficiency
Conditions
Interventions
Intervention group: Visitors to Jahrom University of Medical Sciences' Endocrinology and Ophthalmology Clinic, who also suffer from serum deficiency of 25OHD and dry eye, and the intervention of the p
Sponsors
Jahrom University of Medical Sciences Vice Chancellor for Research
Eligibility
Sex/Gender
All
Age
No minimum to 50 Years
Inclusion criteria
Inclusion criteria: Patients referred to the endocrinology clinic of Jahrom University of Medical Sciences with abnormal serum levels of 25OHD
Exclusion criteria
Exclusion criteria: Patients with SS (Sjogren's Syndrome) or with thyroid disease Having a history of other systemic rheumatic diseases Vitamin A deficiency Glucocorticoid, antidepressant, contraceptive, estrogen People with vitamin B12 deficiency, eye surface disorders and contact lenses, type 1 diabetes Pregnancy, lactation Has a history of eye surgery Individuals with crp above the baseline
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Eye dry. Timepoint: Measure the dryness of the eye at the beginning of the study (before the intervention) and 8 weeks after taking vitamin D tablets. Method of measurement: Using Schirmer's paper in the lower fornix and measuring its wetting rate, TBUT test result (using fluorescein paper in the lower fornix and measuring the discontinuity time of the lacrimal layer), dry eye score in the OSDI questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum level 25OHD. Timepoint: At the beginning of the study (before the start of the intervention) and 8 weeks after the intervention. Method of measurement: Blood sampling and blood tests. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSalma Ahi
Jahrom University of Medical Sciences
Outcome results
None listed