Patients suffered thermal burns in need skin graft. Exposure to unspecified smoke, fire and flames
Conditions
Interventions
Intervention 1: Intervention group: the intervention sites with a thickness of 0.4 to 0.6 mm are given using an electric dermatome with the same level of oxidation
Bleeding is controlled using epinephrine 1 in 50,000 with sterile gauze. One of the donor sites is randomly covered with an amniotic membrane. Amniotic membrane is taken from sero negative mothers who
Bleeding is controlled using epinephrine 1 in 50,000 with sterile gauze. One of the donor sites is accidentally covered with ordinary dressing, ie Vaseline gas (control group).In the control group, th
Sponsors
Zanjan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
7 Years to 60 Years
Inclusion criteria
Inclusion criteria: Patients with second- or third-degree burns or patients who need a semi-thick skin graft for any other reason and have a donor site Donor location in the limbs No injuries other than burns General physical and mental health Age between 7 years and 60 years Other conditions, such as trauma, are less than 40 percent of the wound and are on the limb and need to be removed
Exclusion criteria
Exclusion criteria: Patients with blood-borne viral infections including hepatitis B and C and HIV Dissatisfaction of patients to enter the study Lack of follow-up ability Presence of any cerebrovascular, cardiovascular, endocrine, liver and kidney diseases; Pregnancy History of alcohol and drug abuse Concomitant use of antibiotics (orally and topically) Concomitant use of steroids or immunosuppressive drugs Infected patients at the donor site
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Scar percentage. Timepoint: The amount of scar on the fifth, fourteenth, and finally thirty-sixth days is evaluated as outpatient in the clinic by the relevant professor and its amount is recorded with a qualitative scale of 4 items: excellent, good, average, weak. Method of measurement: A measure of the body's scar level that is measured objectively.;Healing rate. Timepoint: The time required for wound healing on the fifth, fourteenth, and finally 30th days of the clinic is evaluated on an outpatient basis by the relevant professor and its amount is recorded with a qualitative scale of 4 items: excellent, good, average, weak. Method of measurement: Healed: the wound area where the medicine wasapplied is completely healed ObviouslyEffective:70 % of the wound is healed Effective: over 30 % of the wound is healed Ineffective: the effective standard is not met. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMohammad Hosein Moghimi
Zanjan University of Medical Sciences
Outcome results
None listed