Investigation of the effect of interlipid in patients with a history of recurrent implantation failure

The effect of immunotherapy with injectable intervalipide in improving pregnancy outcomes in patients with a history of recurrent implantation failure in assisted reproductive therapies

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200615047781N1

Enrollment

Registered

2020-07-08

Start date

2020-12-28

Completion date

Unknown

Last updated

2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

reccurent implantation failure in assisted reproductive therapies.

Interventions

Intervention group: intervention group, a dose of 2-4 mg 20% intralipid in 250 ml normal saline (Sina Pakhsh Saba Co.Tehran, Iran)was injected a day before progesterone administration and the second d

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Patients referred to Milad Infertility Center in Mashhad with a history of repeated implantation failure

Exclusion criteria

Exclusion criteria: History of fibroids endometrial polyp endometriosis Hydrosalpangs Fat metabolism disorder Allergies to eggs and soy liver disease renal disease pulmonary disease Blood coagulation disorder Genetic diseases and chromosomal disorders anatomic disorders vaginal infections hormonal disorders trombophilia

Design outcomes

Primary

Measure	Time frame
Chemical pregnancy rate. Timepoint: Two weeks after embryo transfer. Method of measurement: serum bhcg level.;Clinical pregnancy rate. Timepoint: 6 weeks after embryo transfer. Method of measurement: sonography.;Abortion rate. Timepoint: Pregnancy loss before 12 weeks of pregnancy. Method of measurement: sonography.	—

Countries

Iran (Islamic Republic of)

Contacts

Public Contactmalihe mahmodi nia

Mashhad University of Medical Sciences

mahmoudiniam@mums.ac.ir+98 51 3853 6169

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026