Infertility with poor ovarian response to ovarian stimulation.
Conditions
Interventions
Intervention 1: Control group: Ovarian stimulation begins on day 2 of the menstrual cycle with Cinnal-f gonadotropin (CinnaGen, Iran). The starting dose of gonadotropin will be individualized based on
Sponsors
Yazd University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 44 Years
Inclusion criteria
Inclusion criteria: infertile women 18-44 years old poor responder to ovarian stimulation according to bologna criteria candidate for ART
Exclusion criteria
Exclusion criteria: Existence of male infertility factor if the sperm is not in the ejaculate and the man is a candidate for sperm extraction by surgery Women with ovarian endometriosis History of hysteroscopic surgery (like asherman or submucosal fibroma) Women with underlying disease(like diabetes mellitus(DM) and cardiac problem) who are prohibited from getting pregnant or undergoing ART at the discretion of the relevant specialist physician
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical pregnancy. Timepoint: 6 weeks after embryo transfer. Method of measurement: Abdominal or vaginal ultrasound and see the gestational sac. | — |
Secondary
| Measure | Time frame |
|---|---|
| Chemical pregnancy. Timepoint: Two weeks after embryo transfer. Method of measurement: Measurement of serum Beta HCG.;Quality of embryo. Timepoint: After embryo formation. Method of measurement: Qualitatively by the embryologist.;Oocyte count. Timepoint: After ovarian puncture. Method of measurement: By an embryologist.;Number of mature oocytes. Timepoint: After ovarian puncture. Method of measurement: By an embryologist.;Number of embryos. Timepoint: After embryo formation. Method of measurement: By an embryologist.;Cycle cancellation rate. Timepoint: During the ovulation stimulation cycle. Method of measurement: Lack of ovarian response after ten days of ovulation stimulation. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactEmami Fatemeh
Yazd University of Medical Sciences
Outcome results
None listed