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Evaluation of the effect of nano micelles containing curcumin (Sina Ccurcumin) as a therapeutic supplement in patients with COVID-19

Evaluation of the effect of nano micelles containing curcumin (Sina Ccurcumin) as a therapeutic supplement in patients with COVID-19 and investigating of immune responses balance changes following treatment: A randomized double blind clinical trial.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200611047735N1
Enrollment
40
Registered
2020-06-19
Start date
2020-07-05
Completion date
Unknown
Last updated
2020-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COVID-19. COVID-19, virus identified

Interventions

Intervention 1: Intervention group: Patients with COVID-19, in addition to routine drug treatment, will receive 40 mg of nano curcumin capsules 4 times a day (one for breakfast, one for lunch, one for

Sponsors

Bandare-abbas University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Laboratory-approved COVID-19 tests (2019-nCoV Real-Time RT-PCR) (preferably at a particular center or university-approved center) regardless of clinical manifestations and close contact history Signing a written consent form No simultaneous participation in other clinical trials

Exclusion criteria

Exclusion criteria: Pregnancy and lactation History of allergy to turmeric or curcumin products Smoking (more than 5 cigarettes a day) Patient connected to the ventilator Clinical evidence for respiratory failure at the time of hospitalization / admission (SaO2 = 90% or PaO2 <8 kPa) Having comorbidities (such as severe renal failure Glomerular filtration rate less than 30 ml / min, liver failure ,Congestive heart failure, or Chronic obstructive pulmonary disease) History of gallstones History of gastritis or active gastrointestinal ulcer

Design outcomes

Primary

MeasureTime frame
Clinical symptoms. Timepoint: On a weekly basis, patients are examined clinically on days 1, 7, and 14. Method of measurement: Clinical examinations.;Immune cell balance. Timepoint: On a weekly basis, blood samples are taken from patients and patients are examined on days 1, 7 and 14. Method of measurement: Molecular experiments.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAmin Reza Nikpoo

Bandare-abbas University of Medical Sciences

nikpoora@hums.ac.ir+98 76 3371 0370

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 25, 2026