The effect of some micronutrients supplementation in treatment of hypothyroidism

The effect of some micronutrients consumption on Thyroid function, lipid profile and glycemic status in hypothyroid patients

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200610047719N1

Enrollment

Registered

2022-01-31

Start date

2022-02-20

Completion date

Unknown

Last updated

2022-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypothyroidism. Hypothyroidism, unspecified

Interventions

Intervention 1: Intervention group: One daily capsule of selenium plus supplement (200 micrograms sodium selenite, 4 mg zinc citrate, 120 mg vitamin C, 100 IU vitamin E , 2500 IU vitamin A) or an alte

Eligibility

Sex/Gender

All

Age

19 Years to 65 Years

Inclusion criteria

Inclusion criteria: Hypothyroid patients who are candidates for levothyroxine Age 19 to 65 years (both male and female) Not to take vitamin D orally or by injection during the last 2-3 months Willingness to participate in the study

Exclusion criteria

Exclusion criteria: History of various thyroid diseases Smoking or taking addictive drugs or alcohol Pregnancy and breastfeeding Chronic renal failure, dialysis, diabetes, other autoimmune diseases and malignancies or taking certain medications Critical condition in the last 3 months leading to hospitalization or cytokine use Taking a variety of multivitamin mineral or antioxidant supplements as well as following a low-calorie diet 3 months before the start of the study Participating in other clinical trials at the same time or recently

Design outcomes

Primary

Measure	Time frame
Thyroid stimulating hormone. Timepoint: Baseline and after intervention. Method of measurement: Blood test.	—

Secondary

Measure	Time frame
Anti thyroid peroxidase. Timepoint: Baseline and after intervention. Method of measurement: Blood test.;Serum triglyceride. Timepoint: Baseline and after intervention. Method of measurement: Blood test.;Serum total cholesterol. Timepoint: Baseline and after intervention. Method of measurement: Blood test.;High density lipoprotein. Timepoint: Baseline and after intervention. Method of measurement: Blood test.;Low density lipoprotein. Timepoint: Baseline and after intervention. Method of measurement: Blood test.;Fasting blood sugar. Timepoint: Baseline and after intervention. Method of measurement: Blood test.;Serum fasting insulin. Timepoint: Baseline and after intervention. Method of measurement: Blood test.;Homeostatic model assessment for insulin resistance. Timepoint: Baseline and after intervention. Method of measurement: Calculation.	—

Measure

Time frame

Anti thyroid peroxidase. Timepoint: Baseline and after intervention. Method of measurement: Blood test.;Serum triglyceride. Timepoint: Baseline and after intervention. Method of measurement: Blood test.;Serum total cholesterol. Timepoint: Baseline and after intervention. Method of measurement: Blood test.;High density lipoprotein. Timepoint: Baseline and after intervention. Method of measurement: Blood test.;Low density lipoprotein. Timepoint: Baseline and after intervention. Method of measurement: Blood test.;Fasting blood sugar. Timepoint: Baseline and after intervention. Method of measurement: Blood test.;Serum fasting insulin. Timepoint: Baseline and after intervention. Method of measurement: Blood test.;Homeostatic model assessment for insulin resistance. Timepoint: Baseline and after intervention. Method of measurement: Calculation.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMehrnaz Nikkhah Bodaghi

Iran University of Medical Sciences

mehrnaznikkhah@yahoo.com+98 21 86701

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026