The effectiveness of curcumin in pain reduction in orthodontic patient

A clinical trial to compare the effectiveness of ibuprofen with curcumin in pain reduction after initial archwire placement in orthodontic patient

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200609047705N1

Enrollment

Registered

2020-06-10

Start date

2020-06-21

Completion date

Unknown

Last updated

2020-06-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Orthodontic. Fitting and adjustment of ileostomy and other intestinal appliances

Interventions

Intervention 1: Intervention group: Intervention group I will receive 400 mg ibuprofen every 8 hours after initial archwire placement. Intervention 2: Intervention group: Intervention group II will re

Eligibility

Sex/Gender

Female

Age

14 Years to 30 Years

Inclusion criteria

Inclusion criteria: Female with aged range 14-30 years No history of systemic disease Nonuse of analgesic

Exclusion criteria

Exclusion criteria: Having a special medical condition Having drug intolerance Having gastrointestinal disorders

Design outcomes

Primary

Measure	Time frame
The pain rate in chewing. Timepoint: 2, 6 hours, and 2 days after the intervention. Method of measurement: Visual Analogue Scale (VAS).;The pain rate in biting. Timepoint: 2, 6 hours, and 2 days after the intervention. Method of measurement: Visual Analogue Scale (VAS).;The pain rate in tipping anterior teeth. Timepoint: 2, 6 hours, and 2 days after the intervention. Method of measurement: Visual Analogue Scale (VAS).;The pain rate in put posterior teeth on each other. Timepoint: 2, 6 hours, and 2 days after the intervention. Method of measurement: Visual Analogue Scale (VAS).	—

Measure

Time frame

The pain rate in chewing. Timepoint: 2, 6 hours, and 2 days after the intervention. Method of measurement: Visual Analogue Scale (VAS).;The pain rate in biting. Timepoint: 2, 6 hours, and 2 days after the intervention. Method of measurement: Visual Analogue Scale (VAS).;The pain rate in tipping anterior teeth. Timepoint: 2, 6 hours, and 2 days after the intervention. Method of measurement: Visual Analogue Scale (VAS).;The pain rate in put posterior teeth on each other. Timepoint: 2, 6 hours, and 2 days after the intervention. Method of measurement: Visual Analogue Scale (VAS).

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Parsa Ghiasi

Mashhad University of Medical Sciences

Parsa.ghiasi73@yahoo.com+98 51 3883 2300

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026