Comparison of the effect of misoprostol alone and misoprostol with Foley catheter in termination of pregnancy in the second trimester

Comparison of the effect of misoprostol and misoprostol with Foley cervical catheter for termination of pregnancy in women undergoing previous cesarean section in the second trimester of pregnancy

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200608047685N3

Enrollment

Registered

2022-04-30

Start date

2022-01-05

Completion date

Unknown

Last updated

2022-05-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Disposal of vaginal products after previous cesarean section in the second trimester of pregnancy.

Interventions

Intervention 1: Intervention group: cases with fetus with FHR receive 200 micrograms of sublingual misoprostol every three hours (maximum 5 doses) until the onset of effective uterine contractions (at

Eligibility

Sex/Gender

Female

Age

18 Years to 45 Years

Inclusion criteria

Inclusion criteria: History of previous cesarean section Gestational age 15-28 weeks Intact membrane No vaginal bleeding Willingness to enter the study

Exclusion criteria

Exclusion criteria: Allergy to prostaglandins Cervical Stenosis A history of more than three cesarean sections

Design outcomes

Primary

Measure	Time frame
Duration from the beginning of the intervention to vaginal delivery. Timepoint: During the intervention. Method of measurement: By the hour and with the help of vaginal examination by hand.	—

Secondary

Measure	Time frame
Vaginal delivery in less than 24 hours. Timepoint: From the beginning of the intervention until 24 hours later. Method of measurement: Per hour and using a questionnaire.;Number of doses of misoprostol. Timepoint: During the intervention. Method of measurement: Questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMasoumeh Mirtaimouri

Mashhad University of Medical Sciences

Mirtaimourim@mums.ac.ir+98 915 310 6875

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026