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The effect of oral cephalexin and metronidazole on reducing cesarean section infection

Effect of post–cesarean delivery oral cephalexin and metronidazole on surgical site infection among obese women

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200608047685N2
Enrollment
420
Registered
2021-03-15
Start date
2019-04-09
Completion date
Unknown
Last updated
2021-04-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cesarean section infection. Disruption of cesarean delivery wound

Interventions

Intervention 1: Intervention group: Receiving 2 g of intravenous cefazolin before skin incision and after 8 hours, the first dose of yellow capsule of oral cefazolin (500 mg) made by Sobhan Pharmaceut

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
15 Years to No maximum

Inclusion criteria

Inclusion criteria: At least 15 years old Body mass index greater than 30 before pregnancy Do not take oral antibiotics for the past month

Exclusion criteria

Exclusion criteria: Reluctance to participate in the study Immune Deficiency Syndrome Having insulin-treated diabetes Rupture of the amniotic sac Allergy to cephalosporins and metronidazole The need to prescribe antibiotics for other reasons in the post-cesarean section

Design outcomes

Primary

MeasureTime frame
Incision site infection. Timepoint: Evaluation 1 and 4 weeks after cesarean section. Method of measurement: Examination and observation.;Uterine tenderness. Timepoint: Evaluation 1 and 4 weeks after cesarean section. Method of measurement: Examination.;Incision opening. Timepoint: Evaluation 1 and 4 weeks after cesarean section. Method of measurement: Examination and observation.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaral Rezaee

Mashhad University of Medical Sciences

RezaeiM941@mums.ac.ir+98 51 3800 2000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 10, 2026