Skip to content

anesthetic effect of Perilocain versus Mepivacain in inferior alveolar nerve block

Comparision of success rate of inferior alveolar nerve block protocol in mandibular first molars with symptomatic irriversible pulpitis by Prilocain and Mepivacain local anaesthesia: A randomized control clinical trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200607047680N1
Enrollment
100
Registered
2020-06-18
Start date
2020-01-21
Completion date
Unknown
Last updated
2020-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Inferior alveolar nerve block.

Interventions

Intervention 1: Intervention group: Inferior alveolar nerve block performed by single-shot injection of 2 cartridges of 3% mepivacaine (manufactured by Inibsa Dental s.t.u co) using a standard syringe

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patients between 18 and 65 years Indication of Root Canal Treatment (RCT) on firs molar tooth Normal periapical appearance Patient's consent to participate in the study Evidence of symptomatic irreversible pulpitis that shows a predominant pain in response to cold pulp sensibility test compared to the control teeth

Exclusion criteria

Exclusion criteria: History of allergy to anesthetic agents (of any kind) Use of painkillers within 6 hours prior to the procedure Use of any kind of medication with possible interaction with anesthetic agents Presence of any pathological lesions at the site of injection Previous history of facial trauma Presence of pathological pocket while probing Patients without response to cold pulp sensibility test Presence of periradicular pathology severe than PDL widening Patients with partial necrosis

Design outcomes

Primary

MeasureTime frame
Level of analgesia based on Visual Analog Scale. Timepoint: 15 minutes after injection. Method of measurement: Visual Analog Scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMahsa Eskandarinezhad

Tabriz University of Medical Sciences

Eskandarinezhadmahsa@yahoo.com+98 41 3335 5965

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026