Evaluation of the effectiveness of traditional medicine combination based on the Ferula assa-foetida gum - Tragacanth in Participants with Moderate to Severe Coronavirus Disease (COVID-19)

A prospective randomized controlled trial comparing the effectiveness of traditional medicine combination based on the Ferula assa-foetida gum - Tragacanth with moderate to severe Coronavirus disease (COVID-19) compared to standard treatment

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200607047675N1

Enrollment

122

Registered

2020-06-15

Start date

2020-06-19

Completion date

Unknown

Last updated

2022-03-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COVID-19. COVID-19

Interventions

Intervention 1: Intervention group: 300mg of soft Ferula gum and 150mg of soft tragacanth gum: twice a day, and the national guidelines for the treatment of COVID-19. Intervention 2: Control group: t

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: PCR confirmed diagnostic chest CT scan Consent for voluntary participation Hospitalization

Exclusion criteria

Exclusion criteria: Patients with end stage heart failure Recent cardiac intervention (less than 2 months): coronary angioplasty, ICD, CABG, Valvuloplasty or replacement Pulmonary fibrosis or advanced COPD End stage kidney or liver disease Pregnant or lactating ladies Patients on immunosuppressive therapy Active tuberculosis Active hepatitis The critical stage of COID19

Design outcomes

Primary

Measure	Time frame
Oxygen saturation (=94% on room air). Timepoint: Day 1 and 14. Method of measurement: pulse oximetry.;Lymphocyte count. Timepoint: Day 1 and 14. Method of measurement: Complete Blood Count.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNayereh Esmaeilzadeh

Mashhad University of Medical Sciences

esmaeilzadehn1@mums.ac.ir+98 51 3841 5222

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026