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Comparison of Efficacy of Nebulized Ketamine with Intravenous Morphine in Patients with Multiple Trauma

Comparison of Efficacy of Nebulized Ketamine with Intravenous Morphine in Patients with Multiple Trauma

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200602047633N1
Enrollment
200
Registered
2020-11-28
Start date
2020-11-21
Completion date
Unknown
Last updated
2021-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with Multiple Trauma.

Interventions

Intervention 1: Intervention group:1 mg / kg ketamine nebulizer with a maximum dose of 50 mg, which is brought to a volume of 3 cc with distilled water and poured into the nebulizer chamber, and conne

Sponsors

Yazd University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to 64 Years

Inclusion criteria

Inclusion criteria: Trauma patients with trauma pain with a pain score greater than 4 Age over 4 years Age less than 65 years

Exclusion criteria

Exclusion criteria: Patients with level of consciousness 13 Housing consumption in the last 4 hours History of seizures Unsatisfied people to participating in the project Psychedelics and drug addiction Maxillofacial trauma in which the patient is unable to use a nebulizer mask Systolic blood pressure less than 90 and more than 180 Respiratory rate less than 10 pulse rate Less than 60 and more than 140 Suspected of bleeding brain lesions or cerebral edema Pregnancy History of allergies to any of the drugs used in the study Frequent nausea and vomiting Brain Tumor Glaucoma

Design outcomes

Primary

MeasureTime frame
Response to treatment by reducing the pain intensity by two points (20 mm) in terms of visual analog scale (VAS). Timepoint: Measurement of pain score at the beginning of the study (before the intervention) and 5, 10, 15, 30 and 60 minutes after the start of treatment. Method of measurement: visual analog scale (VAS).

Secondary

MeasureTime frame
Creating analgesia which patient's intensity pain goes below than 5. Timepoint: Measurement of pain score at the beginning of the study (before the intervention) and 5, 10, 15, 30 and 60 minutes after the start of treatment. Method of measurement: visual analog scale (VAS).;Determining the time to start treatment response in two groups. Timepoint: Measurement of pain score at the beginning of the study (before the intervention) and 5, 10, 15, 30 and 60 minutes after the start of treatment. Method of measurement: visual analog scale (VAS).;Determining the frequency of patients who failed treatment in two groups. Timepoint: At the end of the study. Method of measurement: Calculate the number.;Determine the number of times the drug is prescribed. Timepoint: At the end of the study. Method of measurement: Calculate the number.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZahra Rayat Roknabadi

Yazd University of Medical Sciences

zahra.rayat75@gmail.com+98 35 3237 0718

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026