Condition 1: Diabetes. Condition 2: End stage renal disease. Type 2 diabetes mellitus End stage renal disease
Conditions
Interventions
Intervention 1: Intervention group: receives curcumin 80 mg, daily , for 24 weeks. Intervention 2: Control group: receives placebo.
Sponsors
Kashan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
40 Years to 85 Years
Inclusion criteria
Inclusion criteria: GFR Between 15-89 SBP between 140-160 and DBP between 90-100 mmHg Not pregnant or lactating no history of smoking or alcohol abuse no underlying condition including cardiovascular diseases , cancer , autoimmune disorders and thyroid function abnormalities not having underlying disease that causes proteinuria
Exclusion criteria
Exclusion criteria: underlying diseases that caused admission to hospital High blood pressure using Fluvoxamine or any kind of antioxidant drugs Night worker
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Carotid-femoral pulse wave velocity. Timepoint: Before intervention and 24 weeks after intervention. Method of measurement: Color doppler ultrasound.;Carotid Intima-media thickness. Timepoint: Before intervention and 24 weeks after intervention. Method of measurement: Color doppler ultrasound. | — |
Secondary
| Measure | Time frame |
|---|---|
| Hs-CRP level. Timepoint: before and 24 weeks after intervention. Method of measurement: Blood test. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHamidreza Talari
Kashan University of Medical Sciences
Outcome results
None listed