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Effect of oral health care and mouth rinse in treatment of Covid-19

Efficacy of professional oral health care (POHC) and chlorhexidine and% 0/2 povidon Iodine mouth rinse on survival rate and clinical characteristics of patients with Covid-19

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200527047581N1
Enrollment
200
Registered
2020-08-23
Start date
2020-06-05
Completion date
Unknown
Last updated
2020-09-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

SARS-CoV-2 ?associated SARI. SARS-CoV-2

Interventions

Sponsors

Kashan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: possibility of involving to Covid-19 PaO2/FiO2 50% consciousness of patient and to be able to complete letter of satisfaction minimum 18 years old

Exclusion criteria

Exclusion criteria: Pregnancy Immunodeficiency such as patient with Severe combined immune deficiency and HIV Allergy to mouth rinse ImmunoSuppressant drug consumer such as transplantation recipient patient Dissatisfaction with participating in the study

Design outcomes

Primary

MeasureTime frame
Duration of hospitalization. Timepoint: End of study. Method of measurement: Calculation.;Mortality status. Timepoint: 28 days after admit day. Method of measurement: percent (live/ dead).;Xerostomia. Timepoint: Daily during first day of hospitalization until 28 days. Method of measurement: percent (has/has not).;Change of Taste sens. Timepoint: Daily during first day of hospitalization until 28 days. Method of measurement: percent (has/has not).;New oral erythematous lesion. Timepoint: Daily during first day of hospitalization until 28 days. Method of measurement: percent (has/has not).;New oral ulcer. Timepoint: Daily during first day of hospitalization until 28 days. Method of measurement: percent (has/has not ).

Secondary

MeasureTime frame
Para clinical outcome(White blood cell count). Timepoint: The first day and the last day of discharge. Method of measurement: cell number x 1000.;Para clinical outcome (blood potassium). Timepoint: The first day and the last day of discharge. Method of measurement: milligrams per decilitre.;Para clinical outcome (blood magnesium). Timepoint: The first day and the last day of discharge. Method of measurement: milligrams per decilitre.;Para clinical outcome (platelet count). Timepoint: The first day and the last day of discharge. Method of measurement: cell number x 1000.;Para clinical outcome (C Reactive protein). Timepoint: The first day and the last day of discharge. Method of measurement: milligrams per decilitre.;Para clinical outcome(CURB65)). Timepoint: The first day and the last day of discharge. Method of measurement: scale.;Para clinical outcome (Creatinine). Timepoint: The first day and the last day of discharge. Method of measurement: milligrams per decilitre.;Para clinical outcome(Respiratory rate per minute). Timepoint: The first day and the last day of discharge. Method of measurement: number of breath per minute.;Para clinical outcome(blood pressure). Timepoint: The first day and the last day of discharge. Method of measurement: millimetre of mercury.;Para clinical outcome(Body temperature). Timepoint: The first day and the last day of discharge. Method of measurement: centigrade.;Para clinical outcome (heart rate per minute). Timepoint: The first day and the last day of discharge. Method of measurement: beats per minute.;Para clinical outcome (Blood Urea nitrogen). Timepoint: The first day and the last day of discharge. Method of measurement: milligrams per decilitre.;Para clinical outcome (blood nutriome). Timepoint: The first day and the last day of discharge. Method of measurement: milligrams per decilitre.;Para clinical outcome (Blood glucose). Timepoint: The first day and the last day of discharge. Method of measurement: milligrams per decilitre.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactElaheh GhasemzadehHosseini

Kashan University of Medical Sciences

dr.el.ghasemzade@gmail.com+98 31 5554 8840

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026