knee replacement. Osteoarthritis of knee
Conditions
Interventions
Intervention 1: Intervention group 1: 2 ampoules of 500 mg tranexamic acid, intravenously, One dose, One hour before surgery. Intervention 2: Intervention group 2: 2 ampoules of 500 mg tranexamic aci
Sponsors
Dr. Ali Shariati Hospital/ Orthopedic ward
Eligibility
Sex/Gender
All
Age
53 Years to 84 Years
Inclusion criteria
Inclusion criteria: 1)Patients need total knee replacement 2)Patients have no coagulation problems 3)Patients have no underlying disease 4)Patients have no history of thrombophlebitis 5)Patients compliance to participate in the study
Exclusion criteria
Exclusion criteria: 1)Patients have coagulation problem 2)Patients have history of thrombophlebitis 3)Patients have history of cardiovascular and brain disease 4)Patients non compliance to participate in the study 5)Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The amount of blood collected inside the drains after surgery. Timepoint: 24 hours after surgery. Method of measurement: Measuring the amount of blood collected inside the drains in cm3 (cc). | — |
Secondary
| Measure | Time frame |
|---|---|
| Observation the size of knee hemarthrosis after surgery. Timepoint: 48 hours after surgery. Method of measurement: Observation and examination. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAnis Salimi
School of medicine/Islamic Azad University, Najafabad Branch
Outcome results
None listed