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Treatment of Covid-19 patients with convalescent plasma

Immediate uses of convalescent covid-19 plasma in the treatment of new infected patients at the first day of hospitalization in a clinical trail

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200525047562N1
Enrollment
100
Registered
2020-06-14
Start date
2020-05-25
Completion date
Unknown
Last updated
2020-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COVID-19 disease.

Interventions

Intervention 1: Intervention group: Symptomatic COVID-19 patients who are hospitalized and have Score>4 in terms of WHO Progression Scale. Before 24 hours passed from the hospitalization. A 500 cc uni

Sponsors

High Educational and Research Institute of Transfusion Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Symptomatic COVID-19 patients who are hospitalized and have Score>4 in terms of WHO Progression Scale. The least reasons of hospitalization are dyspnea and/or SPO230 The intervention should be performed within the first 24 hours of hospitalization.

Exclusion criteria

Exclusion criteria: COVID-19 patients having Score<4 in terms of WHO Progression Scale. More than 24 hours passed from hospitalization.

Design outcomes

Primary

MeasureTime frame
Reduce at least 2 points on clinical signs or score less than 3, each earlier. Timepoint: At the beginning of the study (before the start of the intervention) and day 4 of hospitalization, day 7 of hospitalization and discharge time. Method of measurement: WHO Progression Scale.;Length of hospital stay. Timepoint: Hospitalization time to discharge. Method of measurement: Counting days.

Secondary

MeasureTime frame
The rate of need for artificial ventilation and entry into the ICU. Timepoint: From hospitalization to discharge. Method of measurement: Percentage calculation.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSaeed Mohammadi

Iran Blood Transfusion Organization

smohammadi@cina.tums.ac.ir+98 21 8862 3682

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026