Comparison of the antifungal effect of Curcumin and Nystatin in treatment of fungous associated with removable prothesis

Comparison of antifungal effect of Curcumin and Nystatin in denture stomatitis type 2 and type 3

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200519047516N1

Enrollment

Registered

2020-07-24

Start date

2020-10-06

Completion date

Unknown

Last updated

2020-08-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Denture stomatitis. Candidiasis

Interventions

Intervention 1: Intervention group: drug(Curcumin drops prepared from the active ingredient of curcumin in the pharmacology department of the Faculty of Pharmacy, Islamic Azad University-5 cc -4 times

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients above 18 With denture stomatitis; type 2 and 3

Exclusion criteria

Exclusion criteria: Exclusion criteria: patients with allergy to curcumin pregnant breast feeding women changes in immune system chemotherapy radiotherapy patients who take antibiotics and anti fungal drugs within 4 weeks ago

Design outcomes

Primary

Measure	Time frame
Count of cloni. Timepoint: Before intervention-2 weeks after intervention. Method of measurement: Colony forming unit (CFU) with microbiological measurment.;Erythema. Timepoint: Before intervention-2 weeks after intervention. Method of measurement: mm2- measured in photoshop program.	—

Secondary

Measure	Time frame
Erythema. Timepoint: before intervention. Method of measurement: Measurement in millimeters.;Number of Candida albicans colonies. Timepoint: before intervention. Method of measurement: Prepare culture from the patient's mouth and count the number of colonies.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHaniye Meftahpour

Islamic Azad University

haniye.meftahpour@gmail.com+98 21 8863 9044

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026