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Investigation of the effect of intravenous vitamin C on definite patients with coronavirus pneumonia

Interventional study of intravenous vitamin C in definitive patients with covid 19 and its effect on changes in lung CT scan and clinical and laboratory symptoms of patients

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200516047468N1
Enrollment
50
Registered
2020-05-19
Start date
2020-04-08
Completion date
Unknown
Last updated
2020-06-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COVID 19 PNEUMONIA. This code assigned to a disease diagnosis of COVID-19 confirmed by laboratory testing.

Interventions

Intervention 1: Intervention group: In this group of patients, intravenous vitamin C is injected at a dose of 2 grams every 6 hours for five days. The manufacturer of this drug is Iran Daroupakhsh Com

Sponsors

Shahid Beheshti University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients who have a positive corona pcr test. Patients over 18 years of age. Oxygen saturation should be below 93%. The patient's respiratory rate should be more than 30 per minute. Lung involvement in chest or CT scans of the lungs is more than 50 percent.

Exclusion criteria

Exclusion criteria: Allergy to vitamin C The patient's shortness of breath may be due to cardiac pulmonary edema Be pregnant or breastfeeding Have chronic kidney disease Be in diabetic ketoacidosis Have kidney stones

Design outcomes

Primary

MeasureTime frame
The amount of lung involvement in a CT scan: According to the radiologist, the appearance of lung involvement and the percentage of lung involvement are measured. Timepoint: Five days after receiving vitamin C intravenously. Method of measurement: According to the radiologist, the appearance of lung involvement and the extent of lung involvement are scoring.

Secondary

MeasureTime frame
Oxygen saturation rate of patients. Timepoint: Five days after receiving vitamin C intravenously. Method of measurement: Using an pulse oxymeter.;Respiratory rate of patients. Timepoint: Five days after receiving vitamin C intravenously. Method of measurement: Examination by a doctor.;Serum CRP level. Timepoint: Five days after receiving vitamin C intravenously. Method of measurement: Report by Laboratory.;Lymphopenia rate. Timepoint: Five days after receiving vitamin C intravenously. Method of measurement: Report by Laboratory.;Mortality rate. Timepoint: At the end of the patient's hospitalization. Method of measurement: report by doctor.;Duration of hospitalization. Timepoint: At the end of the patient's hospitalization. Method of measurement: Calculated by a physician.;Intubation rate. Timepoint: At the end of the study. Method of measurement: Calculated by the analyzer.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHamideh Moradi Shahr Babak

Shahid Beheshti University of Medical Sciences

hamidehmoradi05@gmail.com+98 34 3411 2418

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026